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merck millipore,默克密理博,480025,NEMO-Binding Domain Binding Peptide, Cell-Permeable - Calbiochem
产品名称:NEMO-Binding Domain Binding Peptide, Cell-Permeable - Calbiochem
产品型号:480025
A cell-permeable Antennapedia-NBD (wild type) fusion peptide that exhibits anti-inflammatory properties.
merck millipore,默克密理博,480025,NEMO-Binding Domain Binding Peptide, Cell-Permeable - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₇₀H₂₅₉N₄₉O₄₂S 描述 概述 A cell-permeable Antennapedia-NBD (wild type) fusion peptide that exhibits anti-inflammatory properties. Acts by inhibiting cytokine-induced NF-κB activation and NF-κB-dependent gene expression. Suggested to block the interaction of NEMO with the IKK (IκB)-kinase complex and thereby prevents NF-κB activation. Does not affect the TNF-α-induced phosphorylation of c-Jun and DNA binding of the transcription factor Oct-1. 产品目录编号 480025 品牌系列 Calbiochem®
同义词 DRQIKIWFQNRRMKWKKTALDWSWLQTE, NBD-Binding Peptide, Cell Permeable 参考 参考 Jimi, E., et al. 2004. Nat. Med., 10, 617.
Siegmund, D., et al. 2001. J. Biol. Chem. 276, 43708.
May, M.J., et al. 2000. Science 289, 1550.
Li, Q., et al. 1999. Science 284, 321.产品信息 具有ATP竞争性 N 形式 White lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₁₇₀H₂₅₉N₄₉O₄₂S 化学配方 C₁₇₀H₂₅₉N₄₉O₄₂S Molar Mass 3693.3 吸湿 Hygroscopic
肽序列 H-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Trp-Ser-Trp-Leu-Gln-Thr-Glu-OH 可逆 N 生物信息 主靶 cytokine-induced NF-κB activation and NF-κB-dependent gene expression 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 肽序列 H-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Trp-Ser-Trp-Leu-Gln-Thr-Glu-OH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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