• merck millipore,默克密理博,480025,NEMO-Binding Domain Binding Peptide, Cell-Permeable - Calbiochem
  • merck millipore,默克密理博,480025,NEMO-Binding Domain Binding Peptide, Cell-Permeable - Calbiochem

    产品名称:NEMO-Binding Domain Binding Peptide, Cell-Permeable - Calbiochem
    产品型号:480025
    A cell-permeable Antennapedia-NBD (wild type) fusion peptide that exhibits anti-inflammatory properties.

    merck millipore,默克密理博,480025,NEMO-Binding Domain Binding Peptide, Cell-Permeable - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,480025,NEMO-Binding Domain Binding Peptide, Cell-Permeable - Calbiochem

    重要规格表

    经验配方
    C₁₇₀H₂₅₉N₄₉O₄₂S
    描述
    概述 A cell-permeable Antennapedia-NBD (wild type) fusion peptide that exhibits anti-inflammatory properties. Acts by inhibiting cytokine-induced NF-κB activation and NF-κB-dependent gene expression. Suggested to block the interaction of NEMO with the IKK (IκB)-kinase complex and thereby prevents NF-κB activation. Does not affect the TNF-α-induced phosphorylation of c-Jun and DNA binding of the transcription factor Oct-1.
    产品目录编号 480025
    品牌系列 Calbiochem®
    同义词 DRQIKIWFQNRRMKWKKTALDWSWLQTE, NBD-Binding Peptide, Cell Permeable
    参考
    参考 Jimi, E., et al. 2004. Nat. Med., 10, 617.
    Siegmund, D., et al. 2001. J. Biol. Chem. 276, 43708.
    May, M.J., et al. 2000. Science 289, 1550.
    Li, Q., et al. 1999. Science 284, 321.
    产品信息
    具有ATP竞争性 N
    形式 White lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₁₇₀H₂₅₉N₄₉O₄₂S
    化学配方 C₁₇₀H₂₅₉N₄₉O₄₂S
    Molar Mass 3693.3
    吸湿 Hygroscopic
    肽序列 H-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Trp-Ser-Trp-Leu-Gln-Thr-Glu-OH
    可逆 N
    生物信息
    主靶 cytokine-induced NF-κB activation and NF-κB-dependent gene expression
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    肽序列 H-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Trp-Ser-Trp-Leu-Gln-Thr-Glu-OH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,480025,NEMO-Binding Domain Binding Peptide, Cell-Permeable - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,04-1065,Anti-phospho-PSD95 (Ser295) Antibody, clone EP2615Y, rabbit monoclonal
下一件merck millipore产品:merck millipore,默克密理博,06-937-I,Anti-phospho-STAT6 Antibody (Tyr641)



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