merck millipore,默克密理愽
  • merck millipore,默克密理博,14-679,HIPK1 Protein, active, 10 µg

  • merck millipore,默克密理博,14-679,HIPK1 Protein, active, 10 µg

    产品名称：HIPK1 Protein, active, 10 µg
    产品型号：14-679
    Active, N-terminal 6His-tagged, recombinant, human HIPK1, amino acids 158-555. For use in Kinase Assays.

    merck millipore,默克密理博,14-679,HIPK1 Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-679,HIPK1 Protein, active, 10 µg

    描述
    产品目录编号 14-679
    品牌系列 Upstate
    商名
    • Upstate
    描述 HIPK1 Protein, active, 10 µg
    概述 N-terminal 6His-tagged, recombinant, human HIPK1, amino acids 158-555.
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, human HIPK1, amino acids 158-555. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 HIPK1 expressed by baculovirus in Sf21 cells.
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_198269.1
    • NM_152696.3
    • NM_181358.1
    • NM_198268.1
    Entrez基因汇总 The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.
    基因符号
    • Myak
    • HIPK1
    • MGC33446
    • KIAA0630
    • Nbak2
    • MGC26642
    • MGC33548
    蛋白靶 HIPK1
    纯化方法 Ni2+/NTA-agarose
    靶子系列 CMGC
    UniProt编号
    • Q86Z02
    UniProt汇总 FUNCTION: SwissProt: Q86Z02 # May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.
    SIZE: 1210 amino acids; 130843 Da
    SUBUNIT: Interacts with Nkx1-2 and Nkx2-5 (By similarity). Interacts with DAXX and TP53.
    SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By similarity). Note=Predominantly nuclear.
    TISSUE SPECIFICITY: Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.
    PTM: Autophosphorylated. Phosphorylated and activated by JNK1.
    SIMILARITY: SwissProt: Q86Z02 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of MBP (13-104).
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C from date of shipment
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-679,HIPK1 Protein, active, 10 µg

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