merck millipore,默克密理愽
  • merck millipore,默克密理博,410960,Ischemin - Calbiochem

  • merck millipore,默克密理博,410960,Ischemin - Calbiochem

    产品名称：Ischemin - Calbiochem
    产品型号：410960
    A cell-permeable azobenzene compound that reversibly targets CBP-BRD acetyl-lysine binding pocket with moderate selectivity over BAZ1B, PCAF, BRD4-1 and BAZ2B.

    merck millipore,默克密理博,410960,Ischemin - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,410960,Ischemin - Calbiochem

    重要规格表

    经验配方
    C₁₅H₁₇N₃SO₄
    描述
    概述 A cell-permeable azobenzene compound that reversibly targets CREB-binding protein bromodomain (CBP-BRD) acetyl-lysine binding pocket (Kd = 19 µM) with moderate selectivity over BAZ1B, PCAF, BRD4-1 and BAZ2B (Kd = 37, 41, 70 and > 100 µM, respectively) and disrupts CBP interaction with the binding partners. Blocks CBP-p53 interaction and alters the post-translational modification states on p53 and histones. Shown to inhibit the transcription functions of p53 on DNA damage (IC50 = 5 µM for p53-induced p21 activation in Luc-U2OS cells) and suppress cardiac myocyte apoptosis during ischemia conditions.
    产品目录编号 410960
    品牌系列 Calbiochem®
    同义词 (E)-5-(2-Amino-4-hydroxy-5-methyl-phenylazo)-2,4-dimethyl-benzenesulfonic acid, MS120, BRD4 Inhibitor II
    参考
    参考 Borah, J.C., et al. 2011, Chem. Biol. 18, 531.
    产品信息
    形式 Orange-red solid
    Hill配方 C₁₅H₁₇N₃SO₄
    化学配方 C₁₅H₁₇N₃SO₄
    Molar Mass 335.4
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Regulatory Review
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,410960,Ischemin - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,35-004,TK Antibody, 20X
下一件merck millipore产品：merck millipore,默克密理博,14-679,HIPK1 Protein, active, 10 µg


相关产品

merck millipore,默克密理博,SF-1622,miR-375; Human, Cyanine 3 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1622,miR-375; Human, Cyanine 3 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,ABF201,Anti-TRIF Antibody merck millipore,默克密理博,ABF201,Anti-TRIF Antibody

merck millipore,默克密理博,SF-1250,S100A9; Ms, Cyanine 3 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1250,S100A9; Ms, Cyanine 3 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,200488,InSolution™Bestatin, Hydrochloride - Calbiochem merck millipore,默克密理博,200488,InSolution™Bestatin, Hydrochloride - Calbiochem

merck millipore,默克密理博,35-004,TK Antibody, 20X merck millipore,默克密理博,35-004,TK Antibody, 20X

merck millipore,默克密理博,14-679,HIPK1 Protein, active, 10 µg merck millipore,默克密理博,14-679,HIPK1 Protein, active, 10 µg

merck millipore,默克密理博,ABN164,Anti-IL22RA2 Antibody merck millipore,默克密理博,ABN164,Anti-IL22RA2 Antibody

merck millipore,默克密理博,MAB1976X,Anti-Integrin αVβ3 Antibody, clone LM609, Alexa Fluor488 conjugated merck millipore,默克密理博,MAB1976X,Anti-Integrin αVβ3 Antibody, clone LM609, Alexa Fluor488 conjugated

merck millipore,默克密理博,MABF321,Anti-CD45 (mouse) Antibody, PE, clone 30-F11 merck millipore,默克密理博,MABF321,Anti-CD45 (mouse) Antibody, PE, clone 30-F11

merck millipore,默克密理博,70726,Tuner™ Competent Cell Set - Novagen merck millipore,默克密理博,70726,Tuner™ Competent Cell Set - Novagen


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部