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描述 产品目录编号 14-660 品牌系列 Upstate
商名 - Upstate
描述 Itk Protein, active, 10 µg 概述 N-terminal 6His-tagged, recombinant, human Itk, amino acids 352-617. 应用 应用 Active, N-terminal 6His-tagged, recombinant, human Itk, amino acids 352-617. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Human Itk expressed by baculovirus in Sf21 cells. 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_005546.3
Entrez基因汇总 This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. 基因符号 - MGC126257
- ITK
- LYK
- PSCTK2
- EMT
- MGC126258
蛋白靶 Itk 纯化方法 Ni2+/NTA-agarose 靶子系列 TK UniProt编号 - Q08881
UniProt汇总 FUNCTION: SwissProt: Q08881 # Plays a role in T-cell proliferation and differentiation.
COFACTOR: Binds 1 zinc ion per subunit (By similarity).
SIZE: 620 amino acids; 71831 Da
SUBCELLULAR LOCATION: Cell membrane (By similarity). Note=Localizes to cell surface receptors in the plasma membrane after stimulation with respective receptors (TCR, CD28, CD2) in T- cells (By similarity).
TISSUE SPECIFICITY: T-cell lines and natural killer cell lines.
SIMILARITY: SwissProt: Q08881 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily. & Contains 1 Btk-type zinc finger. & Contains 1 PH domain. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of MBP. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 10 µg 包装 2 vials at 5μg each
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