merck millipore,默克密理愽
  • merck millipore,默克密理博,14-608,ZIPK Protein, active, 10 µg

  • merck millipore,默克密理博,14-608,ZIPK Protein, active, 10 µg

    产品名称：ZIPK Protein, active, 10 µg
    产品型号：14-608
    Active, N-terminal, GST tagged, recombinant, of human ZIPK amino acids 1-290, for use in Kinase Assays.

    merck millipore,默克密理博,14-608,ZIPK Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-608,ZIPK Protein, active, 10 µg

    描述
    产品目录编号 14-608
    品牌系列 Upstate
    商名
    • Upstate
    描述 ZIPK Protein, active, 10 µg
    概述 N-terminal, GST tagged, recombinant, of human ZIPK amino acids 1-290
    应用
    应用 Active, N-terminal, GST tagged, recombinant, of human ZIPK amino acids 1-290, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed in E. coli
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_001348.1
    Entrez基因汇总 Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis.
    基因符号
    • ZIP
    • DAPK3
    • FLJ36473
    • ZIP-kinase
    • ZIPK
    • Dlk
    蛋白靶 ZIPK
    纯化方法 Glutathione agarose affinity chromatography
    靶子系列 CAMK
    UniProt编号
    • O43293
    UniProt汇总 FUNCTION: SwissProt: O43293 # Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis.
    COFACTOR: Magnesium.
    SIZE: 454 amino acids; 52536 Da
    SUBUNIT: Homodimer or forms heterodimers with ATF4. Both interactions require an intact leucine zipper domain and oligomerization is required for full enzymatic activity. Also binds to DAXX and PAWR, possibly in a ternary complex which plays a role in caspase activation. Interacts with AATF and CDC5L.
    SUBCELLULAR LOCATION: Nucleus. Cytoplasm (By similarity). Note=Relocates to the cytoplasm on binding PAWR where the complex appears to interact with actin filaments (By similarity). Associates to centromeres from prophase to anaphase.
    SIMILARITY: SwissProt: O43293 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of 250μM ZIPtide
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-608,ZIPK Protein, active, 10 µg

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下一件merck millipore产品：merck millipore,默克密理博,AX45005TC,AXIS™ Axon Isolation Device, 450 µm


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