merck millipore,默克密理博,14-579,DDR2 Protein, active, 10 µg

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merck millipore,默克密理博,14-579,DDR2 Protein, active, 10 µg
产品名称：DDR2 Protein, active, 10 µg
产品型号：14-579
Active, N-terminal His6-tagged, recombinant, human DDR2 amino acids 467-end, for use in Kinase Assays.

merck millipore,默克密理博,14-579,DDR2 Protein, active, 10 µg

产品介绍

merck millipore,默克密理博,14-579,DDR2 Protein, active, 10 µg

描述
产品目录编号	14-579
品牌系列	Upstate
商名	Upstate
描述	DDR2 Protein, active, 10 µg
概述	N-terminal His6-tagged, recombinant, human DDR2 amino acids 467-end

应用
应用	Active, N-terminal His6-tagged, recombinant, human DDR2 amino acids 467-end, for use in Kinase Assays.
主要应用	Kinase Assay

生物信息
来源	expressed by baculovirus in Sf21 insect cells
品种	Human
特异活性	For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez基因编号	NM_006182.2 NM_001014796.1
Entrez基因汇总	Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
基因符号	MIG20a DDR2 TYRO10 TKT NTRKR3
蛋白靶	DDR2
纯化方法	Ni²⁺/NTA-agarose
靶子系列	TK
UniProt编号	Q16832
UniProt汇总	FUNCTION: SwissProt: Q16832 # This tyrosine kinase receptor for fibrillar collagen mediates fibroblast migration and proliferation. Contributes to cutaneous wound healing (By similarity). SIZE: 855 amino acids; 96752 Da SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: The major 10 kDa transcript is expressed in high levels in heart and lung, less in brain, placenta, liver, skeletal muscle, pancreas, and kidney. SIMILARITY: SwissProt: Q16832 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. & Contains 1 F5/8 type C domain. & Contains 1 protein kinase domain.

产品使用声明
质量保证	routinely evaluated by phosphorylation of Axltide
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	6 months at -70°C

包装信息
数量	10 µg
包装	Also available in 250 µg size --call for pricing and availability and reference catalog number 14-579M when ordering the 250 µg size.

merck millipore,默克密理博,14-579,DDR2 Protein, active, 10 µg

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