merck millipore,默克密理博,14-568,Fgr Protein, active, 10 µg

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Merck Millipore 默克密理愽

描述
产品目录编号	14-568
品牌系列	Upstate
商名	Upstate
描述	Fgr Protein, active, 10 µg
概述	N-terminal His6-tagged, recombinant, human Fgr, amino acids 2-end

应用
应用	Active, N-terminal His6-tagged, recombinant, human Fgr, amino acids 2-end, for use in Kinase Assays.
主要应用	Kinase Assay

生物信息
来源	Expressed by baculovirus in Sf21 insect cells
品种	Human
特异活性	For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez基因编号	NM_005248.2 NM_001042729.1 NM_001042747.1
Entrez基因汇总	This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
基因符号	FLJ43153 FGR P55-FGR p58c-fgr MGC75096 c-src2 p55c-fgr SRC2 c-fgr
蛋白靶	Fgr
纯化方法	Ni²⁺/NTA-agarose
靶子系列	TK
UniProt编号	P09769
UniProt汇总	SIZE: 529 amino acids; 59479 Da SUBUNIT: Binds PTPNS1 (By similarity). SIMILARITY: SwissProt: P09769 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.

产品使用声明
质量保证	Routinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	6 months at -70°C

包装信息
数量	10 µg
包装	Also available in 250 µg size --call for pricing and availability and reference catalog number 14-568M when ordering the 250 µg size.

merck millipore,默克密理博,14-568,Fgr Protein, active, 10 µg

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