• merck millipore,默克密理博,371958,H-8, Dihydrochloride
  • merck millipore,默克密理博,371958,H-8, Dihydrochloride

    产品名称:H-8, Dihydrochloride
    产品型号:371958
    A potent, cell-permeable, reversible, and ATP-competitive inhibitor of cyclic-nucleotide-dependent protein kinases.

    merck millipore,默克密理博,371958,H-8, Dihydrochloride

  • 产品介绍
  • merck millipore,默克密理博,371958,H-8, Dihydrochloride

    重要规格表

    经验配方 CAS号
    C₁₂H₁₅N₃O₂S · 2HCl113276-94-1
    描述
    概述 A potent, cell-permeable, reversible, and ATP-competitive inhibitor of cyclic-nucleotide-dependent protein kinases. Inhibits protein kinase A (Ki = 1.2 µM), myosin light chain kinase (Ki = 68 µM), protein kinase C (Ki = 15 µM), and protein kinase G (Ki = 480 nM).
    产品目录编号 371958
    品牌系列 Calbiochem®
    同义词 N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide, 2HCl, PKA Inhibitor I
    参考
    参考 Ido, M., et al. 1991. Br. J. Cancer 64, 1103.
    Hagiwara, M., et al. 1987. Mol. Pharmacol. 31, 523.
    Inagaki, M., et al. 1986. Mol. Pharmacol. 29, 577.
    Hidaka, H., et al. 1984. Biochemistry 23, 5036.
    产品信息
    CAS号 113276-94-1
    具有ATP竞争性 Y
    形式 Lyophilized
    Hill配方 C₁₂H₁₅N₃O₂S · 2HCl
    化学配方 C₁₂H₁₅N₃O₂S · 2HCl
    Molar Mass 338.3
    可逆 Y
    结构配方图像
    生物信息
    主靶 MLCK
    主靶Ki 68 µM against MLCK
    纯度 >95% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    无需冷冻 No
    特殊指南 Following reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 6 months at 4°C.

    merck millipore,默克密理博,371958,H-8, Dihydrochloride

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