• merck millipore,默克密理博,14-519M,Cdk6/Cyclin D3 Protein, active, 250 µg
  • merck millipore,默克密理博,14-519M,Cdk6/Cyclin D3 Protein, active, 250 µg

    产品名称:Cdk6/Cyclin D3 Protein, active, 250 µg
    产品型号:14-519M
    Active, N-terminal, His6-tagged full length human Cdk6 complexed with N-terminal GST-tagged full-length human Cyclin D3, for use in Kinase Assays.

    merck millipore,默克密理博,14-519M,Cdk6/Cyclin D3 Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-519M,Cdk6/Cyclin D3 Protein, active, 250 µg

    描述
    产品目录编号 14-519M
    品牌系列 Upstate
    商名
    • Upstate
    描述 Cdk6/Cyclin D3 Protein, active, 250 µg
    概述 N-terminal, His6-tagged fulllength human cdk6 complexed with N-terminal GSTtagged full-length human cyclin D3
    应用
    应用 Active, N-terminal, His6-tagged full length human Cdk6 complexed with N-terminal GST-tagged full-length human Cyclin D3, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed in Sf21 cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_001259.5
    Entrez基因汇总 The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.
    基因符号
    • MGC59692
    • CDK6
    • PLSTIRE
    蛋白靶 CDK6/cyclinD3
    纯化方法 Glutathione-agarose
    靶子系列 CMGC
    UniProt编号
    • Q00534
    UniProt汇总 FUNCTION: SwissProt: Q00534 # Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins.
    SIZE: 326 amino acids; 36938 Da
    SIMILARITY: SwissProt: Q00534 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of histone H1
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 250 µg
    包装 Also available in 10 μg size (cat#14-519) and in bulk (cat# 14-519-K).

    merck millipore,默克密理博,14-519M,Cdk6/Cyclin D3 Protein, active, 250 µg

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