merck millipore,默克密理博,5677,Spermine, Tetrahydrochloride - CAS 306-67-2

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merck millipore,默克密理博,5677,Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem
产品名称：Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem
产品型号：5677
Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.

merck millipore,默克密理博,5677,Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem

产品介绍

merck millipore,默克密理博,5677,Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem

重要规格表

经验配方	CAS号
C₁₀H₂₆N₄ . 4HCl	306-67-2

描述
概述	Polyamine that plays an important role in the regulation of cellular proliferation and differentiation. Has both stimulatory and inhibitory effects on NMDA receptors depending on the subunit composition of the receptor. Acts as an inhibitor of phospholipase Cα and an activator of phospholipase Cδ. Inhibits DNA fragmentation and morphological apoptosis. Inhibits neuronal NOS.
产品目录编号	5677
品牌系列	Calbiochem®

参考
参考	Igarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101. Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075. Hu, J., et al. 1994. Neurosci. Lett. 175, 41. Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208. Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085. Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141. Ask, A., et al. 1992. Cancer Lett. 66, 29. Chida, N., et al. 1992. Brain Res. 593, 57. Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428. Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585. Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328. Shantz, L.M., et al. 1992. Biochem. J. 288, 511.

参考

Igarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101.
Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075.
Hu, J., et al. 1994. Neurosci. Lett. 175, 41.
Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208.
Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085.
Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141.
Ask, A., et al. 1992. Cancer Lett. 66, 29.
Chida, N., et al. 1992. Brain Res. 593, 57.
Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428.
Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585.
Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328.
Shantz, L.M., et al. 1992. Biochem. J. 288, 511.

产品信息
CAS号	306-67-2
形式	White solid
Hill配方	C₁₀H₂₆N₄ . 4HCl
化学配方	C₁₀H₂₆N₄ . 4HCl
Molar Mass	348.3
结构配方图像

生物信息
主靶	phospholipase C α
副靶	nNOS
纯度	≥99% by titration

理化信息
溶解度	H₂O

GHS安全信息
RTECS	EJ7230000

安全信息
R相	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S相	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Irritant
储存	+15°C to +30°C
无需冷冻	No
特殊指南	Following reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C under inert gas.