merck millipore,默克密理愽
  • merck millipore,默克密理博,14-486,p70 S6 Kinase Protein, active, 10 µg

  • merck millipore,默克密理博,14-486,p70 S6 Kinase Protein, active, 10 µg

    产品名称：p70 S6 Kinase Protein, active, 10 µg
    产品型号：14-486
    Active, N-terminal His6-tagged, recombinant amino acids 1-421 of human p70 S6 kinase, for use in Kinase Assays.

    merck millipore,默克密理博,14-486,p70 S6 Kinase Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-486,p70 S6 Kinase Protein, active, 10 µg

    描述
    产品目录编号 14-486
    品牌系列 Upstate
    商名
    • Upstate
    描述 p70 S6 Kinase Protein, active, 10 µg
    概述 N-terminal His6-tagged, recombinant amino acids 1-421 of human p70 S6 kinase
    应用
    应用 Active, N-terminal His6-tagged, recombinant amino acids 1-421 of human p70 S6 kinase, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 Expressed in Sf21 cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_003161.2,T412E
    Entrez基因汇总 This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.
    基因符号
    • PS6K
    • RPS6KB1
    • p70-alpha
    • p70S6k
    • p70-S6K
    • p70
    • S6K
    • S6Kalpha)
    • P70S6K
    • STK14A
    • S6K1
    • p70(S6K)-alpha
    蛋白靶 p70S6K
    纯化方法 Ni2+/NTA-agarose
    靶子系列 AGC
    UniProt编号
    • P23443
    UniProt汇总 FUNCTION: SwissProt: P23443 # Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens.
    SIZE: 525 amino acids; 59140 Da
    SUBUNIT: Interacts with PPP1R9A/neurabin-1 (By similarity).
    SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell junction, synapse, synaptosome (By similarity).
    TISSUE SPECIFICITY: Widely expressed.
    SIMILARITY: SwissProt: P23443 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 Routinely evaluated by phosphorylation of S6 Kinase/Rsk-2 Substrate Peptide 2
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 10 µg
    包装 Also available in 250μg size as catalog # 14-486M.

    merck millipore,默克密理博,14-486,p70 S6 Kinase Protein, active, 10 µg

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