- 当前位置:首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
描述 产品目录编号 14-326 品牌系列 Upstate
商名 - Upstate
描述 Src Protein, active, 10 µg 概述 N-Terminal His6-tagged, recombinant, full-length, human Src. 应用 应用 Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Human c-src, expressed in Sf21 cells. 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_198291.1
- NM_005417.3
Entrez基因汇总 This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. 基因符号 - pp60c-src
- SRC
- ASV
- c-src
- p60-Src
- SRC1
- c-SRC
蛋白靶 Src 纯化方法 Ni2+/NTA-agarose 靶子系列 TK UniProt编号 - P12931
UniProt汇总 SIZE: 536 amino acids; 59835 Da
SUBUNIT: Interacts with DDEF1/ASAP1 via its SH3 domain. Interacts with CCPG1 (By similarity). Interacts with CDCP1, PELP1, TGFB1I1 and TOM1L2.
PTM: Phosphorylated on Tyr-530 by c-Src kinase (CSK). The phosphorylated form is termed pp60c-src. The phosphorylated tail interacts with the SH2 domain thereby repressing kinase activity.
SIMILARITY: SwissProt: P12931 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 Routinely evaluated by phosphorylation of Src Substrate Peptide 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -70°C 包装信息 数量 10 µg 包装 2 vials at 5μg each
Also available in 250μg size (2x125μg)--call for pricing and availability and reference catalog number 14-326M when ordering the 250μg size.
上一件merck millipore产品:merck millipore,默克密理博,16-283,Anti-MAP Kinase 1/2 (Erk1/2) Antibody, CT, Alexa Fluor 488 conjugate
下一件merck millipore产品:merck millipore,默克密理博,SF-1797,MEN1; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,362338,Glyco-SNAP-1 - Calbiochem
merck millipore,默克密理博,FCCH100109,FlowCellect MitoStress Kit
merck millipore,默克密理博,MAB3086,Anti-Ryanodine Receptor Antibody, clone RYR.1
merck millipore,默克密理博,HTS055M,ChemiSCREEN™ Membrane Preparation Recombinant Human CXCR5 Chemokine Recep...
merck millipore,默克密理博,16-283,Anti-MAP Kinase 1/2 (Erk1/2) Antibody, CT, Alexa Fluor 488 conjugate
merck millipore,默克密理博,SF-1797,MEN1; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,HTS013RTA,Ready-to-Assay™ CCR8 Chemokine Family Receptor Frozen Cells
merck millipore,默克密理博,AP113-K,Goat anti-Human IgG Fc, Affinity Purified (1mg) KC
merck millipore,默克密理博,124018,Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbio...
merck millipore,默克密理博,HND2MAG-39K,MILLIPLEX MAP Human Neurological Disorders Magnetic Bead Panel 2 - Ne...



