merck millipore,默克密理愽
  • merck millipore,默克密理博,124019,Akt Inhibitor IX, API-59CJ-OMe - CAS 98510-80-6 - Calbiochem

  • merck millipore,默克密理博,124019,Akt Inhibitor IX, API-59CJ-OMe - CAS 98510-80-6 - Calbiochem

    产品名称：Akt Inhibitor IX, API-59CJ-OMe - CAS 98510-80-6 - Calbiochem
    产品型号：124019
    The Akt Inhibitor IX, API-59CJ-OMe, also referenced under CAS 98510-80-6, controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylati More>>

    merck millipore,默克密理博,124019,Akt Inhibitor IX, API-59CJ-OMe - CAS 98510-80-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,124019,Akt Inhibitor IX, API-59CJ-OMe - CAS 98510-80-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₁H₂₂N₂O₃ • 3H₂O98510-80-6
    描述
    概述 A cell-permeable ellipticine compound that potently and selectively induces apoptosis in human endometrial cancer cells (RL95-2 and Ishikawa) that exhibit elevated Akt activity (effective concentration = 12-24 µM), but not on cells with low Akt activity. Directly affects the activity by Akt, but not the level of cellular phosphorylation of Akt, ERK1/2, JNK1/2, PDK1, PKC isoforms, or serum and glucocorticoid-inducible kinase (SGK).
    产品目录编号 124019
    品牌系列 Calbiochem®
    同义词 MMEA, 9-Methoxy-2-methylellipticinium acetate, NSC 627505
    参考
    参考 Jin, X., et al. 2004. Br. J. Cancer 91, 1808.
    产品信息
    CAS号 98510-80-6
    具有ATP竞争性 N
    形式 Orange red solid
    Hill配方 C₂₁H₂₂N₂O₃ • 3H₂O
    化学配方 C₂₁H₂₂N₂O₃ • 3H₂O
    Molar Mass 404.5
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 Akt
    主靶IC50 12-24 µM against Akt
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,124019,Akt Inhibitor IX, API-59CJ-OMe - CAS 98510-80-6 - Calbiochem

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