• merck millipore,默克密理博,100105,A23187, Free Acid, Streptomyces chartreusensis - CAS 52665-69-7 - Calbiochem
  • merck millipore,默克密理博,100105,A23187, Free Acid, Streptomyces chartreusensis - CAS 52665-69-7 - Calbiochem

    产品名称:A23187, Free Acid, Streptomyces chartreusensis - CAS 52665-69-7 - Calbiochem
    产品型号:100105
    A mobile ion-carrier that forms stable complexes with divalent cations.

    merck millipore,默克密理博,100105,A23187, Free Acid, Streptomyces chartreusensis - CAS 52665-69-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,100105,A23187, Free Acid, Streptomyces chartreusensis - CAS 52665-69-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₉H₃₇N₃O₆52665-69-7
    描述
    概述 A mobile ion-carrier that forms stable complexes with divalent cations. Useful for increasing intracellular Ca2+ levels. Also acts as an uncoupler of oxidative phosphorylation and inhibitor of mitochondrial ATPase activity. An antibiotic with weak activity against Gram-positive bacteria. Also induces apoptosis in mouse lymphoma cell line (S49); however, A23187 has been shown to block apoptosis in other systems, such as when interleukin-3 (IL-3) is withdrawn from IL-3-dependent cells.
    产品目录编号 100105
    品牌系列 Calbiochem®
    同义词 Calcimycin
    参考
    参考 Caron-Leslie, L.A., et al. 1994. FASEB J. 8, 639.
    Saunders, M.J., and Hepler, P.K. 1982. Science 217, 943.
    Pressman, B.C. 1976. Annu. Rev. Biochem. 45, 501.
    Pfeiffer, D.R., et al. 1974. Biochemistry 13, 4007.
    Reed, P.W., and Lardy, H.A. 1972. J. Biol. Chem. 247, 6970.
    产品信息
    CAS号 52665-69-7
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₉H₃₇N₃O₆
    化学配方 C₂₉H₃₇N₃O₆
    Molar Mass 523.6
    可逆 N
    结构配方图像
    生物信息
    主靶 Mitochondrial ATPase
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or MeOH
    GHS安全信息
    RTECS DM4676000
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 26-36/37/39

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing, gloves and eye/face protection.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

    merck millipore,默克密理博,100105,A23187, Free Acid, Streptomyces chartreusensis - CAS 52665-69-7 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,555558,Rho/SRF Pathway Inhibitor, CCG-1423 - CAS 285986-88-1 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,MAB5438,Anti-Neurofibromin Antibody



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