merck millipore,默克密理愽
  • merck millipore,默克密理博,100065,2-APB - CAS 524-95-8 - Calbiochem

  • merck millipore,默克密理博,100065,2-APB - CAS 524-95-8 - Calbiochem

    产品名称：2-APB - CAS 524-95-8 - Calbiochem
    产品型号：100065
    A cell-permeable modulator of Ins(1,4,5)P3-induced Ca2+ release.

    merck millipore,默克密理博,100065,2-APB - CAS 524-95-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,100065,2-APB - CAS 524-95-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₄H₁₆BNO524-95-8
    描述
    概述 A cell-permeable modulator of Ins(1,4,5)P3-induced Ca2+ release. Inhibits Ins(1,4,5)P3-induced Ca2+ release from rat cerebellar microsomal preparations (IC50 = 42 µM) without affecting [3H]-Ins(1,4,5)P3 binding to its receptor. Does not affect Ca2+ release from the ryanodine-sensitive Ca2+ store in rat leg skeletal muscle and heart. Inhibits spontaneous as well as the phasic contractions induced by uterotonic agents. Also reported to inhibit angiotensin II-induced contractions in aortic muscles.
    产品目录编号 100065
    品牌系列 Calbiochem®
    同义词 2-Aminoethoxydiphenylborate, (2-Aminoethoxy)diphenylborane
    参考
    参考 Brooke, R. T., et al. 2004. Lab. Invest. 84, 29.
    Gregory, R.B., et al. 2001. Biochem. J. 354, 285.
    Ma, H.T., et al. 2001. J. Biol. Chem. 276, 18888.
    Ascher-Landsberg, S., et al. 1999. Biochem. Biophys. Res. Commun. 264, 979.
    Maruyama, T., et al. 1997. J. Biochem. 122, 498.
    产品信息
    CAS号 524-95-8
    具有ATP竞争性 N
    形式 White crystalline solid
    Hill配方 C₁₄H₁₆BNO
    化学配方 C₁₄H₁₆BNO
    Molar Mass 225.1
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 Ins(1,4,5)P3-induced Ca2+ release
    主靶IC50 42 µM against Ins(1,4,5)P3-induced Ca2+ release from rat cerebellar microsomal preparations
    纯度 ≥97% by titration
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    GHS安全信息
    RTECS ED6150000
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,100065,2-APB - CAS 524-95-8 - Calbiochem

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