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merck millipore,默克密理博,09-874,Anti-SAP30 (yeast) Antibody
产品名称：Anti-SAP30 (yeast) Antibody
产品型号：09-874
Anti-SAP30 (yeast) Antibody is a Rabbit Polyclonal Antibody for detection of SAP30 (yeast) also known as Sin3 corepressor complex subunit SAP30 & has been validated in WB.
merck millipore,默克密理博,09-874,Anti-SAP30 (yeast) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Yeast (S. cerevisiae) WB Rb Purified Polyclonal Antibody 描述 产品目录编号 09-874 描述 Anti-SAP30 (yeast) Antibody Alternate Names - histone deacetylase complex subunit SAP30
- Sin3 corepressor complex subunit SAP30
- Sin3-associated polypeptide, 30 kDa
- Sin3-associated polypeptide, 30kDa
- Sin3A-associated protein, 30kDa
- Sin3A-associated protein
- 30kDa
背景信息 SAP30 (Sin3A-associated protein) is a widely expressed nuclear protein that is functionally conserved between human and yeast. It is a component of the multiprotein histone deacetylase complex containing the transcriptional repressor Sin3, multiple histone deacetylases (HDAC1 and HDAC2), histone binding proteins (RbAp46 and RbAp48) and other polypeptides. SAP30 can recruit the deacetylase complex to promoter DNA in a Sin3 independent manner and is involved in the recruitment of the mSin3 complex to a specific subset of N-CoR corepressor complexes. The latter function suggests a role for SAP30 in N-CoR-mediated repression. Furthermore, SAP30 may be involved in imparting target specificity to the deacetylase complex. 产品信息 格式 Purified 控制 - Yeast extract
演示 Protein A purified IgG in 0.1M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% NaN3. 应用 应用 Anti-SAP30 (yeast) Antibody is a Rabbit Polyclonal Antibody for detection of SAP30 (yeast) also known as Sin3 corepressor complex subunit SAP30 & has been validated in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Immunogen was a synthetic peptide corresponding to a.a. 141-157 of yeast SAP30, conjugated to KLH. 表位 a.a. 141-157 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes yeast SAP30 at ~27 kDa. 品种反应性 Yeast (S. cerevisiae) Species Reactivity Note Yeast (Saccharomyces cerevisiae). Not tested in other species. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_003864.3
Entrez基因汇总 Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq]
基因符号 - SAP30
UniProt编号 - P38429
UniProt汇总 FUNCTION: Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the
N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
SUBUNIT:Component of the RPD3C(L) complex composed of at least ASH1, CTI6, DEP1, PHO23, RPD3, RXT2, RXT3, SAP30, SDS3, SIN3, UME1 and UME6.
SUBCELLULAR LOCATION: Nucleus.
MISCELLANEOUS: Present with 704 molecules/cell in log phase SD medium.
SIMILARITY: Belongs to the SAP30 family.
产品使用声明 质量保证 Western Blot Analysis:
1 μg/ml of this antibody detected SAP30 in a yeast extract.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of shipment. 包装信息 数量 100 µg
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