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经验配方 CAS号 C₇H₈N₂O₃ 151606-30-3 描述 概述 Protein tyrosine phosphatase inhibitor. Competitively inhibits protein tyrosine phosphatase activity in membrane preparations from human neoplastic T cell line (IC50 = 7.7 µM). Reported to mobilize intracellular calcium stores. Could serve as a stable NO donor for S-nitrosylation of proteins. 产品目录编号 263200 品牌系列 Calbiochem®
同义词 PTP Inhibitor VII 参考 参考 Lajas, A.I., et al. 2000. Mol. Cell Biochem. 205, 163.
Guo, Z., et al. 1996. Bioorganic Med. Chem. Lett. 6, 573.
Watanabe, T., et al. 1995. J. Antibiot. 48, 1460.
Yu, L., et al. 1995. Bioorg. Med. Chem. Lett. 9, 1003.
Imoto, M., et al. 1993. J. Antibiot. 46, 1342.产品信息 CAS号 151606-30-3 具有ATP竞争性 Y 形式 Brown powder Hill配方 C₇H₈N₂O₃ 化学配方 C₇H₈N₂O₃ Molar Mass 168.2 可逆 N 结构配方图像 生物信息 主靶 protein tyrosine phosphatase activity from human neoplastic cell line 主靶IC50 7.7 µM against protein tyrosine phosphatase activity in membrane preparations from human neoplastic T cell line 纯度 ≥90% by HPLC 来源 Streptomyces sp. 理化信息 细胞可渗透 N 溶解度 Chloroform, DMSO, or MeOH GHS安全信息 RTECS CZ9021800 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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