merck millipore,默克密理博,07-804,Anti-phospho-c-Kit (Tyr721) Antibody

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merck millipore,默克密理博,07-804,Anti-phospho-c-Kit (Tyr721) Antibody
产品名称：Anti-phospho-c-Kit (Tyr721) Antibody
产品型号：07-804
This Anti-phospho-c-Kit (Tyr721) Antibody is validated for use in WB for the detection of phospho-c-Kit (Tyr721).

merck millipore,默克密理博,07-804,Anti-phospho-c-Kit (Tyr721) Antibody

产品介绍

merck millipore,默克密理博,07-804,Anti-phospho-c-Kit (Tyr721) Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	07-804
品牌系列	Upstate
商名	Upstate
描述	Anti-phospho-c-Kit (Tyr721) Antibody
Alternate Names	KIT, CD117, PBT, SCFR, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog KIT CD117 PBT SCFR

产品信息
格式	Affinity Purified
演示	100 μL of affinity purified rabbit polyclonal IgG in 50% storage buffer (PBS (without Mg²⁺ and Ca²⁺), pH 7.3 containing 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide) and 50% glycerol.

应用
应用	This Anti-phospho-c-Kit (Tyr721) Antibody is validated for use in WB for the detection of phospho-c-Kit (Tyr721).
主要应用	Western Blotting

生物信息
免疫原品种	Peptide corresponding to amino acid region encompassing the human phospho-c-Kit (Tyr721).
宿主	Rabbit
特异性	Recognizes phosphorylated c-Kit (Tyr721)
同种型	IgG
品种反应性	Human
Species Reactivity Note	Mouse and Rat have not been tested, but are expected to react based on sequence similarity.
抗体类型	Polyclonal Antibody
Entrez基因编号	NM_001093772.1 NM_000222.2
Entrez基因汇总	This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
基因符号	c-kit KIT C-Kit PBT CD117 SCFR
修改	Phosphorylation
纯化方法	Immunoaffinity purified
UniProt编号	P10721
UniProt汇总	FUNCTION: SwissProt: P10721 # This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K). SIZE: 976 amino acids; 109865 Da SUBUNIT: Interacts with APS. Interacts with the tenth PDZ domain of MPDZ. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. DISEASE: SwissProt: P10721 # Defects in KIT are a cause of piebaldism [MIM:172800]. Piebaldism is an autosomal dominant genetic developmental abnormality of pigmentation characterized by congenital patches of white skin and hair that lack melanocytes. & Defects in KIT are a cause of gastrointestinal stromal tumor (GIST) [MIM:606764]. & Defects in KIT have been associated with testicular tumors [MIM:273300]. It includes germ cell tumor (GCT) or testicular germ cell tumor (TGCT). SIMILARITY: SwissProt: P10721 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 5 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.

产品使用声明
质量保证	Routinely evaluated by immunoblot.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 2 years at -20°C from date of shipment. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerolcontaining solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 2 years at -20°C from date of shipment.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerolcontaining solutions to become frozen during storage.