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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-546 品牌系列 Upstate
商名 - Upstate
描述 Anti-ADAP/SLAP-130/Fyb Antibody 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 Anti-ADAP/SLAP-130/Fyb Antibody is an antibody against ADAP/SLAP-130/Fyb for use in WB & IP. 主要应用 - Western Blotting
生物信息 免疫原品种 synthetic peptide corresponding to amino acids 755-768 of mouse Fyn binding protein (ADAP/SLAP-130/Fyb) 宿主 Rabbit 特异性 ADAP/SLAP-130/Fyb 同种型 IgG 品种反应性 Mouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001465
基因符号 - SLAP-130
- FYB
- SLAP130
- FYB-120/130
- p120/p130
- PRO0823
- ADAP
纯化方法 Protein A purfied UniProt编号 - O15117
UniProt汇总 FUNCTION: SwissProt: O15117 # Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
SIZE: 783 amino acids; 85421 Da
SUBUNIT: Part of a complex consisting of SKAP2, FYB and PTPNS1. Part of a complex consisting of SKAP2, FYB and LILRB3 (By similarity). Interacts with FYN, LCP2, SKAP1 and SKAP2.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus (By similarity).
TISSUE SPECIFICITY: Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
PTM: T-cell receptor ligation leads to increased tyrosine phosphorylation.
SIMILARITY: SwissProt: O15117 ## Contains 1 SH3 domain.产品使用声明 质量保证 routinely evaluated by immunoblot in RIPA lysates from RAW 264.7 macrophage cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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