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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-488 品牌系列 Upstate
商名 - Upstate
描述 Anti-PKD2 Antibody Alternate Names - nPKC-D2
- Serine/threonine-protein kinase D2
产品信息 格式 Affinity Purified 控制 - PMA stimulated A431 cells
演示 Immunoaffinity purified rabbit IgG in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl and 0.05% sodium azide as a preservative. 应用 应用 Anti-PKD2 Antibody detects level of PKD2 & has been published & validated for use in WB. 主要应用 - Western Blotting
应用说明 Immunoblot Analysis: A 1:500-1:1,000 dilution of this antibody detected PKD2 in RIPA lysates from A431 cells that had been stimulated with PMA. 生物信息 免疫原品种 KLH-conjugated, synthetic peptide corresponding to amino acids 850-865 (GLPTDRDLGGACPPQD) of human protein kinase D2 (PKD2). 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes PKD2. 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000297
Entrez基因汇总 The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. 基因符号 - HSPC187
- PRKD2
- DKFZP586E0820
- PKD2
- nPKC-D2
纯化方法 Immunoaffinity purified UniProt编号 - Q9BZL6
UniProt汇总 FUNCTION: SwissProt: Q9BZL6 # Calcium-independent, phospholipid-dependent, serine- and threonine-specific protein kinase.
SIZE: 878 amino acids; 96722 Da
TISSUE SPECIFICITY: Widely expressed.
PTM: Autophosphorylated. Phorbol esters stimulates autophosphorylation. Phosphorylation of Ser-876 correlates with the activation status of the kinase.
SIMILARITY: SwissProt: Q9BZL6 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 PH domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain.产品使用声明 质量保证 Routinely evaluated by immunoblot in RIPA lysates from HEK293m cells that had been stimulated with 50 ng/mL of PDBu for 10 minutes or PMA stimulated A431 cells. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 1 year at 2 to 8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 200 µL
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