merck millipore,默克密理愽
  • merck millipore,默克密理博,07-208,Anti-AIF (Apoptosis Inducing Factor) Antibody

  • merck millipore,默克密理博,07-208,Anti-AIF (Apoptosis Inducing Factor) Antibody

    产品名称：Anti-AIF (Apoptosis Inducing Factor) Antibody
    产品型号：07-208
    Anti-AIF (Apoptosis Inducing Factor) Antibody detects level of AIF (Apoptosis Inducing Factor) & has been published & validated for use in WB.

    merck millipore,默克密理博,07-208,Anti-AIF (Apoptosis Inducing Factor) Antibody

  • 产品介绍
  • merck millipore,默克密理博,07-208,Anti-AIF (Apoptosis Inducing Factor) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 07-208
    Replaces 04-430
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-AIF (Apoptosis Inducing Factor) Antibody
    产品信息
    格式 Purified
    演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
    应用
    应用 Anti-AIF (Apoptosis Inducing Factor) Antibody detects level of AIF (Apoptosis Inducing Factor) & has been published & validated for use in WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 peptide corresponding to amino acids 593-606 of human Apoptosis Inducing Factor, AIF (C-KDGEQHEDLNEVAK), containing a N-terminal cysteine
    宿主 Rabbit
    特异性 AIF
    同种型 IgG
    品种反应性 RatHumanMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_004208
    Entrez基因汇总 This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
    基因符号
    • AIF
    • AIFM1
    • MGC111425
    • PDCD8
    纯化方法 Protein A chromatography
    UniProt编号
    • O95831
    UniProt汇总 FUNCTION: SwissProt: O95831 # Probable oxidoreductase that acts as a caspase- independent mitochondrial effector of apoptotic cell death. Extramitochondrial AIF induces nuclear chromatin condensation and large scale DNA fragmentation (in vitro).
    COFACTOR: FAD.
    SIZE: 613 amino acids; 66901 Da
    SUBUNIT: Binds to DNA in a sequence-independent manner.
    SUBCELLULAR LOCATION: Mitochondrion intermembrane space. Nucleus. Note=Translocated to the nucleus upon induction of apoptosis.
    SIMILARITY: SwissProt: O95831 ## Belongs to the FAD-dependent oxidoreductase family.
    产品使用声明
    质量保证 routinely evaluated by immunoblot on a mouse liver preparation
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 2 years at -20°C
    包装信息
    数量 200 µg

    merck millipore,默克密理博,07-208,Anti-AIF (Apoptosis Inducing Factor) Antibody

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