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merck millipore,默克密理博,07-1538,Anti-JMJD4 (NT) Antibody
产品名称：Anti-JMJD4 (NT) Antibody
产品型号：07-1538
Use Anti-JMJD4 (N-terminus) Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC, ELISA to detect JMJD4 (N-terminus) also known as Jumonji domain-containing protein 4.
merck millipore,默克密理博,07-1538,Anti-JMJD4 (NT) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H ELISA, WB, ICC Rb Purified Polyclonal Antibody 描述 产品目录编号 07-1538 描述 Anti-JMJD4 (NT) Antibody Alternate Names - jumonji domain containing 4
- JMJD
- Jumonji domain-containing protein 4
背景信息 Covalent modification of histones plays critical role in regulating chromatin structure and transcription. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that remove specific methyl marks from histones. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
JMJD4 is a transcription factor that is a putative histone demethylase. It is highly expressed in lymphoid (spleen) and hemopoietic (bone marrow) tissues产品信息 格式 Purified 控制 - A431 lysate
演示 Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. 应用 应用 Use Anti-JMJD4 (N-terminus) Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC, ELISA to detect JMJD4 (N-terminus) also known as Jumonji domain-containing protein 4. 主要应用 - ELISA
- Western Blotting
- Immunocytochemistry
应用说明 ELISA:
This antibody was reported by an outside laboratory to be suitable for ELISA.
Immunocytochemistry:
HeLa and NIH/3T3 cells incubated with anti-JMJD4 (N-terminus) stained positively on nuclei.
生物信息 免疫原品种 The immunogen was a KLH-conjugated synthetic peptide corresponding to the N-terminal region of human JMJD4. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the N-terminal region of human JMJD4. 品种反应性 MouseHuman Species Reactivity Note Human and mouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_075383.1
基因符号 - OTTHUMP00000035836
- FLJ12517
- MGC129896
纯化方法 Protein G chromatography UniProt编号 - Q9H9V9
UniProt汇总 SEQUENCE SIMILARITIES: Contains 1 JmjC domain.
CAUTION: It is uncertain whether Met-1 or Met-47 is the initiator.
产品使用声明 质量保证 Western Blot Analysis:
1:250 dilution of this antibody detected JMJD4 on 10 µg of A431 lysate使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 6 months at 2-8°C from date of receipt. For long term storage, store at -20ºC. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. 包装信息 数量 100 µg
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