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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 06-983 品牌系列 Upstate
商名 - Upstate
描述 Anti-GADS Antibody 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%. 应用 应用 Anti-GADS Antibody is an antibody against GADS for use in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated, synthetic peptide corresponding to amino acids 174-188 of murine GADS (GEEIRPSVNRKLSDH) 宿主 Rabbit 特异性 GADS 同种型 IgG 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_004810
Entrez基因汇总 This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist. 基因符号 - OTTHUMP00000028837
- GRAP2
- GRB2L
- GADS
- GRBX
- GrbX
- GRBLG
- GRAP-2
- Mona
- P38
- GRPL
- Grf40
- GRID
- Grf-40
纯化方法 Protein A chromatography UniProt编号 - O75791
UniProt汇总 FUNCTION: SwissProt: O75791 # Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
SIZE: 330 amino acids; 37909 Da
SUBUNIT: Interacts with phosphorylated LIME1 upon TCR activation (By similarity). Interacts with phosphorylated LAT and LAX1 upon TCR activation. Interacts with SHB.
SIMILARITY: SwissProt: O75791 ## Belongs to the GRB2/sem-5/DRK family. & Contains 1 SH2 domain. & Contains 2 SH3 domains.产品使用声明 质量保证 routinely evaluated by immunoblot on Jurkat RIPA cell lysate 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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