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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN271 Replaces MABE510 描述 Anti-TARDBP Antibody Alternate Names - TARDBP
- TAR DNA-binding protein 43
- TDP-43
背景信息 TAR DNA-binding protein 43 (TARDBP) belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in TARDBP have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease. 产品信息 格式 Affinity Purified 控制 - K562 cell lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide and 50% glycerol. 应用 应用 This TARDBP antibody is validated for use in WB, IHC & IF for the detection of the TARDBP protein. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected TARDBP in glioma tissue.
Immunofluorescence Analysis: A 1:50 dilution from a representative lot detected TARDBP in MCF-7 cells.
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human TARDBP. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - TDP43
- TARDBP
纯化方法 Antigen Affinity purified UniProt编号 - Q13148
产品使用声明 质量保证 Evaluated by Western Blotting in K562 cell lysate.
Western Blotting Analysis: A 1:1,500 dilution of this antibody detected TARDBP in 30 µg of K562 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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