merck millipore,默克密理愽
  • merck millipore,默克密理博,06-872,Anti-IRAK Antibody

  • merck millipore,默克密理博,06-872,Anti-IRAK Antibody

    产品名称：Anti-IRAK Antibody
    产品型号：06-872
    Detect IRAK using this Anti-IRAK Antibody validated for use in IP & WB.

    merck millipore,默克密理博,06-872,Anti-IRAK Antibody

  • 产品介绍
  • merck millipore,默克密理博,06-872,Anti-IRAK Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HWBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 06-872
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-IRAK Antibody
    产品信息
    格式 Purified
    控制
    • Positive Control Included: HeLa Nuclear Extract (12-309).
    演示 Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
    应用
    应用 Detect IRAK using this Anti-IRAK Antibody validated for use in IP & WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 Peptide (DRQGPEESDEFQS) corresponding to amino acids 700-712 of human IRAK
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes IRAK.
    同种型 IgG
    品种反应性 MouseHuman
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001569
    Entrez基因汇总 This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    基因符号
    • IRAK-1
    • IRAK1
    • IRAK
    • pelle
    纯化方法 Ammonium sulfate precipitation and DEAE-cellulose chromatography
    UniProt编号
    • P51617
    UniProt汇总 FUNCTION: SwissProt: P51617 # Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Isoform 1 binds rapidly but is then degraded allowing isoform 2 to mediate a slower, more sustained response to the cytokine. Isoform 2 is inactive suggesting that the kinase activity of this enzyme is not required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.
    COFACTOR: Magnesium.
    SIZE: 712 amino acids; 76537 Da
    SUBUNIT: IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1. Interacts with IL1RL1.
    TISSUE SPECIFICITY: Isoform 1 and isoform 2 are ubiquitously expressed in all tissues examined, with isoform 1 being more strongly expressed than isoform 2.
    PTM: Autophosphorylated or is transphosphorylated by IRAK4 following recruitment to the IL-1RI. In the case of isoform 1, this is linked to ubiquitination and degradation.
    SIMILARITY: SwissProt: P51617 ## Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by immunoblot on HeLa nuclear extract
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 200 µg

    merck millipore,默克密理博,06-872,Anti-IRAK Antibody

上一件merck millipore产品：merck millipore,默克密理博,MABC130,Anti-LYVE-1 Antibody, clone 11A9.1
下一件merck millipore产品：merck millipore,默克密理博,HTS092RTA,Ready-to-Assay™ EP3 Prostanoid Receptor Frozen Cells


相关产品

merck millipore,默克密理博,HTS171RTA,Ready-to-Assay™ sst3 Somatostatin Family Receptor Frozen Cells merck millipore,默克密理博,HTS171RTA,Ready-to-Assay™ sst3 Somatostatin Family Receptor Frozen Cells

merck millipore,默克密理博,MABE76,Anti-phospho-Histone H3 (Ser28) Antibody, clone HTA28 merck millipore,默克密理博,MABE76,Anti-phospho-Histone H3 (Ser28) Antibody, clone HTA28

merck millipore,默克密理博,09-814,Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) merck millipore,默克密理博,09-814,Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25)

merck millipore,默克密理博,LSKS09604,测序反应物纯化试剂盒96 merck millipore,默克密理博,LSKS09604,测序反应物纯化试剂盒96

merck millipore,默克密理博,MABC130,Anti-LYVE-1 Antibody, clone 11A9.1 merck millipore,默克密理博,MABC130,Anti-LYVE-1 Antibody, clone 11A9.1

merck millipore,默克密理博,HTS092RTA,Ready-to-Assay™ EP3 Prostanoid Receptor Frozen Cells merck millipore,默克密理博,HTS092RTA,Ready-to-Assay™ EP3 Prostanoid Receptor Frozen Cells

merck millipore,默克密理博,676495,VEGF Inhibitor, V1 - Calbiochem merck millipore,默克密理博,676495,VEGF Inhibitor, V1 - Calbiochem

merck millipore,默克密理博,MAB4371,Anti-SNAI2 Antibody, clone 2B6 merck millipore,默克密理博,MAB4371,Anti-SNAI2 Antibody, clone 2B6

merck millipore,默克密理博,178452,Apolipoprotein A-I, Human Plasma, High-Density Lipoprotein merck millipore,默克密理博,178452,Apolipoprotein A-I, Human Plasma, High-Density Lipoprotein

merck millipore,默克密理博,MAB810R-500UG,Anti-Cytomegalovirus Antibody, clone 8B1.2 merck millipore,默克密理博,MAB810R-500UG,Anti-Cytomegalovirus Antibody, clone 8B1.2


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部