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  • merck millipore,默克密理博,06-236,Anti-Giα1/2 Antibody

  • merck millipore,默克密理博,06-236,Anti-Giα1/2 Antibody

    产品名称：Anti-Giα1/2 Antibody
    产品型号：06-236
    Detect Giα1/2 using this Anti-Giα1/2 Antibody validated for use in IC, IP & WB.

    merck millipore,默克密理博,06-236,Anti-Giα1/2 Antibody

  • 产品介绍
  • merck millipore,默克密理博,06-236,Anti-Giα1/2 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, B, H, MWB, ICCRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 06-236
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-Giα1/2 Antibody
    产品信息
    格式 Purified
    控制
    • Widely expressed
    演示 Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
    应用
    应用 Detect Giα1/2 using this Anti-Giα1/2 Antibody validated for use in IC, IP & WB.
    主要应用
    • Western Blotting
    • Immunocytochemistry
    生物信息
    免疫原品种 10 residue synthetic peptide (KNNLKDCGLF) corresponding to the c-terminus of Gia1 and Gia2
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes Giα1 and Giα2.
    同种型 IgG
    品种反应性 RatBovineHumanMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_002069
    Entrez基因汇总 Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs (MIM 139320) and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain (GNAO1; MIM 139311); and transducin-1 (GNAT1; MIM 139330) and transducin-2 (GNAT2; MIM 139340), proteins involved in phototransduction in retinal rods and cones, respectively (Sullivan et al., 1986 [PubMed 3092218]; Bray et al., 1987 [PubMed 3110783]). Suki et al. (1987) [PubMed 2440724] concluded that the human genome contains at least 3 nonallelic genes for alpha-i-type subunits of G protein; see, e.g, GNAI2 (MIM 139360), GNAI3 (MIM 139370), and GNAIH (MIM 139180).[supplied by OMIM]
    基因符号
    • Gi
    • GNAI1
    纯化方法 Protein A purfied
    UniProt编号
    • P63096
    UniProt汇总 FUNCTION: SwissProt: P63096 # Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli.
    SIZE: 354 amino acids; 40361 Da
    SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1 (By similarity).
    SIMILARITY: SwissProt: P63096 ## Belongs to the G-alpha family. G(i/o/t/z) subfamily.
    产品使用声明
    质量保证 routinely evaluated by immunoblot on Rat Brain Microsomal Preparation or solubilized plasma membranes from mouse 3T3/A31 fibroblasts
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,06-236,Anti-Giα1/2 Antibody

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