merck millipore,默克密理愽
  • merck millipore,默克密理博,MABT123,Anti-Pirh2 Antibody, clone 11G8.1

  • merck millipore,默克密理博,MABT123,Anti-Pirh2 Antibody, clone 11G8.1

    产品名称：Anti-Pirh2 Antibody, clone 11G8.1
    产品型号：MABT123
    Anti-Pirh2 Antibody, clone 11G8.1 is a highly specific mouse monoclonal antibody & that targets Pirh2 & has been tested in western blotting.

    merck millipore,默克密理博,MABT123,Anti-Pirh2 Antibody, clone 11G8.1

  • 产品介绍
  • merck millipore,默克密理博,MABT123,Anti-Pirh2 Antibody, clone 11G8.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT123
    描述 Anti-Pirh2 Antibody, clone 11G8.1
    Alternate Names
    • hPirh2
    • RING finger and CHY zinc finger domain-containing protein 1
    • Androgen receptor N-terminal-interacting protein
    • CH-rich-interacting match with PLAG1
    • E3 ubiquitin-protein ligase Pirh2
    • RING finger protein 199
    • Zinc finger protein 363
    • p53-induced RING-H2 protein
    背景信息 Pirh2, also known as Androgen receptor N-terminal-interacting protein or CH-rich-interacting match with PLAG1 or E3 ubiquitin-protein ligase Pirh2 or RING finger protein 199 or Zinc finger protein 363 or p53-induced RING-H2 protein (Pirh2), encoded by the gene RCHY1/ARNIP/CHIMP/PIRH2/RNF199/ZNF363, is an E3 ubiquitin ligase protein that mediates the E3-dependent ubiquitination and proteasomal degradation of a number of important signaling and DNA methylation proteins including p53/TP53, p73, HDAC1 and CDKN1B. Pirh2 also monoubiquitinates the translesion DNA polymerase POLH and contributes to the regulation of the cell cycle progression. Additionally, Pirh2 increases androgen receptor transcription factor activity as well and Interacts with AR, p53/TP53, MDM2, HDAC1, KAT5, PLAG1, PLAGL2, CDKN1B, COPE, UBE2D2 and GORAB/NTKLBP1 proteins. Pirh2 is localized to the cytoplasm and nucleus, and can be found in nucleus speckles. Pirh2 is expressed in all cell types examined and is up-regulated during the S phase of the cell cycle. Pirh2 is expressed at low levels during G phase.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Pirh2 Antibody, clone 11G8.1 is a highly specific mouse monoclonal antibody & that targets Pirh2 & has been tested in western blotting.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human Pirh2.
    克隆 11G8.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2aκ
    品种反应性 MouseHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_056251
    基因符号
    • ZNF363
    • RCHY1
    • ARNIP
    • CHIMP
    • PIRH2
    • RNF199
    纯化方法 Protein G purified
    UniProt编号
    • Q96PM5
    产品使用声明
    质量保证 Evaluated by Western Blotting in H1299 cell lysate.

    Western Blotting Analysis: 1.0 µg/mL of this antibody detected Pirh2 in 10 µg of H1299 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABT123,Anti-Pirh2 Antibody, clone 11G8.1

上一件merck millipore产品：merck millipore,默克密理博,506171,PlGF-2, Mouse, Recombinant
下一件merck millipore产品：merck millipore,默克密理博,361311,Glycodeoxycholic Acid, Sodium Salt - CAS 16409-34-0 - Calbiochem


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