- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,06-1367,Anti-SRp75 Antibody
产品名称：Anti-SRp75 Antibody
产品型号：06-1367
Anti-SRp75 Antibody is a rabbit polyclonal antibody for detection of SRp75 also known as serine/arginine-rich splicing factor 4, SR splicing factor 4, Pre-mRNA-splicing factor SRP75 & has been validat More>>
merck millipore,默克密理博,06-1367,Anti-SRp75 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Purified Polyclonal Antibody 描述 产品目录编号 06-1367 描述 Anti-SRp75 Antibody Alternate Names - Pre-mRNA-splicing factor SRP75
- serine/arginine-rich splicing factor 4
- splicing factor, arginine/serine-rich 4
- SR splicing factor 4
背景信息 SRp75, also known as Serine/arginine-rich splicing factor 4, is an essential splicing factor that is a member of the SR family of proteins. This protein is a component of the pre-mRNA splicing complex and is believed to play a role in alternative splice site selection. Consistent with this excess levels of SRp75 have been shown to play a role in alternative splicing of CD45. SRp75 is normally found in the nucleus and is known to be hyperphosphorylated at serine residues in its RS domain. 产品信息 格式 Purified 控制 - L6 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-SRp75 Antibody is a rabbit polyclonal antibody for detection of SRp75 also known as serine/arginine-rich splicing factor 4, SR splicing factor 4, Pre-mRNA-splicing factor SRP75 & has been validated in WB. 主要应用 - Western Blotting
应用说明 Immunoprecipitation Analysis: A reprentative lot of this antibody was used by an independent laboratory in IP. (Jiang, K., et al. (2009). Endocrinology. 150(5):2087-2097.) 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human SRp75. 宿主 Rabbit 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with human, mouse, and rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005617
Entrez基因汇总 This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq]. 基因符号 - SRSF4
- SRP001LB
- SRP75
- SFRS4
纯化方法 Protein A UniProt编号 - Q08170
UniProt汇总 FUNCTION: A probable role in alternative splice site selection during pre-mRNA splicing.
SUBUNIT STRUCTURE: Found in a pre-mRNA splicing complex with SRSF4/SFRS4, SRSF5/SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Interacts with PNN.
SUBCELLULAR LOCATION: Nucleus speckle
PTM: Extensively phosphorylated on serine residues in the RS domain.
SEQUENCE SIMILARITIES: Belongs to the splicing factor SR family.
Contains 2 RRM (RNA recognition motif) domains.产品使用声明 质量保证 Evaluated by Western Blot in L6 cell lysate.
Western Blot Analysis: 1:500 dilution of this antibody detected SRp75 on 10 µg of L6 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,SF-1393,ATR; Human, Cyanine 5 RNA Detection Probe,SmartFlare
下一件merck millipore产品：merck millipore,默克密理博,05-581,Anti-CFTR Antibody, clone MM13-4
相关产品
merck millipore,默克密理博,MAB5422,Anti-Choline Acetyltransferase Antibody
merck millipore,默克密理博,CBA086,Glucose Assay Kit
merck millipore,默克密理博,MAB2060,Anti-Integrin β4 Antibody, clone ASC-9
merck millipore,默克密理博,MABN689,Anti-ARHGDIA Antibody, clone 2G3
merck millipore,默克密理博,SF-1393,ATR; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,05-581,Anti-CFTR Antibody, clone MM13-4
merck millipore,默克密理博,05-1559,Anti-PI3 Kinase Antibody, p110γ, clone 17D7.2
merck millipore,默克密理博,05-727,Anti-Rsf-1 Antibody, clone 5H2/E4
merck millipore,默克密理博,05-647,Anti-Tyrosinase Antibody, clone T311
merck millipore,默克密理博,0500-0300,Guava PCA Advanced Assay Suite (5+ Modules)