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merck millipore,默克密理博,MAB5422,Anti-Choline Acetyltransferase Antibody
产品名称：Anti-Choline Acetyltransferase Antibody
产品型号：MAB5422
Anti-Choline Acetyltransferase Antibody detects level of Choline Acetyltransferase & has been published & validated for use in ELISA & WB.
merck millipore,默克密理博,MAB5422,Anti-Choline Acetyltransferase Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB, ELISA M Purified Monoclonal Antibody 描述 产品目录编号 MAB5422 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Choline Acetyltransferase Antibody Alternate Names - ChAT
产品信息 格式 Purified 演示 Purified immunoglobulin. Liquid in 0.02M Phosphate buffer containing 0.25M NaCl and 0.1% sodium azide. 应用 应用 Anti-Choline Acetyltransferase Antibody detects level of Choline Acetyltransferase & has been published & validated for use in ELISA & WB. 主要应用 - Western Blotting
- ELISA
应用说明 Western blot
ELISA
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Recombinant human ChAT. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Reacts with Choline O-Acetyltransferase (ChAT), human. 同种型 IgG 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_020986.2
- NM_020549.3
- NM_020984.2
- NM_020985.2
Entrez基因汇总 Cholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants have been found that contain alternative 5' untranslated exons. Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein. 基因符号 - EC 2.3.1.6
- CHAT
- ChAT
- CMS1A2
- CHOACTase
- CMS1A
UniProt编号 - P28329
UniProt汇总 FUNCTION: SwissProt: P28329 # Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
SIZE: 748 amino acids; 82568 Da
DISEASE: SwissProt: P28329 # Defects in CHAT are the cause of familial infantile myasthenia gravis 2 (FIMG2) [MIM:254210, 254200]; also known as CMS-EA. FIMG2 patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Inheritance is autosomal recessive.
SIMILARITY: SwissProt: P28329 ## Belongs to the carnitine/choline acetyltransferase family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 µg
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