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品种反应性 主要应用 宿主 格式 抗体类型 Xn, H, M WB M Purified Monoclonal Antibody 描述 产品目录编号 05-596 品牌系列 Upstate
商名 - Upstate
描述 Anti-Cdk2 Antibody, clone AN4.3 产品信息 格式 Purified 演示 0.07M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide, and 30% glycerol. 应用 应用 Detect Cdk2 with Anti-Cdk2 Antibody, clone AN4.3 (Mouse Monoclonal Antibody), that has been shown to work in IP & WB. 主要应用 - Western Blotting
应用说明 0.5-2μg/ml of this lot detected cdk2 in HeLa nuclear extract. 4μg of a previous lot immunoprecipitated cdk2 from 500μg of mouse 3T3 nuclear extract. 生物信息 免疫原品种 Recombinant human cdk2 克隆 clone AN4.3 宿主 Mouse 特异性 cdk2, does not react with other cdks 同种型 IgG 品种反应性 XenopusHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001798
Entrez基因汇总 The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. 基因符号 - p33(CDK2)
- CDK2
纯化方法 Protein G chromatography UniProt编号 - P24941
UniProt汇总 FUNCTION: SwissProt: P24941 # Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.
SIZE: 298 amino acids; 33930 Da
SUBUNIT: Found in a complex with CABLES1, CCNA1 and CCNE1. Interacts with CABLES1 (By similarity). Interacts with UHRF2. Part of a complex consisting of UHRF2, CDK2 and CCNE1. Interacts with the Speedy/Ringo proteins SPDYA and SPDYC. Found in a complex with both SPDYA and CDKN1B/KIP1.
SIMILARITY: SwissProt: P24941 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by immunoblot on HeLa nuclear extract 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
上一件merck millipore产品：merck millipore,默克密理博,07-2066,Anti-DOT1L Antibody
下一件merck millipore产品：merck millipore,默克密理博,MAB10041,Mouse Anti-Rat Cytochrome P450 CYP3A4 Antibody, 3A1, 3A11
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