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品种反应性 主要应用 宿主 格式 抗体类型 Vrt WB M Purified Monoclonal Antibody 描述 产品目录编号 05-555 品牌系列 Upstate
商名 - Upstate
描述 Anti-Giα1 Antibody, clone 7H7 产品信息 格式 Purified 演示 0.07M Tris-glycine, pH 7.4, 0.105M NaCl, containing 30% glycerol 应用 应用 Anti-Giα1 Antibody, clone 7H7 detects level of Giα1 & has been published & validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Peptide corresponding to residues 110-123 of Giα1 克隆 7H7 宿主 Mouse 特异性 Giα1 同种型 IgG2b 品种反应性 Vertebrates 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002069
Entrez基因汇总 Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs (MIM 139320) and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain (GNAO1; MIM 139311); and transducin-1 (GNAT1; MIM 139330) and transducin-2 (GNAT2; MIM 139340), proteins involved in phototransduction in retinal rods and cones, respectively (Sullivan et al., 1986 [PubMed 3092218]; Bray et al., 1987 [PubMed 3110783]). Suki et al. (1987) [PubMed 2440724] concluded that the human genome contains at least 3 nonallelic genes for alpha-i-type subunits of G protein; see, e.g, GNAI2 (MIM 139360), GNAI3 (MIM 139370), and GNAIH (MIM 139180).[supplied by OMIM] 基因符号 - Gi
- GNAI1
纯化方法 Protein G chromatography UniProt编号 - P63096
UniProt汇总 FUNCTION: SwissProt: P63096 # Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli.
SIZE: 354 amino acids; 40361 Da
SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1 (By similarity).
SIMILARITY: SwissProt: P63096 ## Belongs to the G-alpha family. G(i/o/t/z) subfamily.产品使用声明 质量保证 routinely evaluated by immunoblot on rat brain microsomal preparation 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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