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品种反应性 主要应用 宿主 格式 抗体类型 H ICC M Purified Monoclonal Antibody 描述 产品目录编号 05-246 品牌系列 Upstate
商名 - Upstate
描述 Anti-Integrin α1 Antibody, clone 5E8D9 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl 应用 应用 Anti-Integrin α1 Antibody, clone 5E8D9 is an antibody against Integrin α1 for use in IC, NEUT. 主要应用 - Immunocytochemistry
生物信息 免疫原品种 Purified human integrinα1 克隆 5E8D9 宿主 Mouse 特异性 integrinα1 同种型 IgG2a 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_181501
Entrez基因汇总 This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. 基因符号 - VLA-1
- ITGA1
- CD49a
- VLA1
纯化方法 Protein A chromatography UniProt编号 - P56199
UniProt汇总 FUNCTION: SwissProt: P56199 # Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen.
SIZE: 1179 amino acids; 130848 Da
SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-1 associates with beta-1.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
DOMAIN: SwissProt: P56199 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain.产品使用声明 质量保证 routinely evaluated on cold ethanol fixed cells in immunocytochemistry 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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