merck millipore,默克密理博,AB9084,Anti-Polycystin-L Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M	IHC, WB, ICC	Rb	Serum	Polyclonal Antibody

产品信息
格式	Serum
控制	POSITIVE CONTROL: adult mouse retina NEGATIVE CONTROL: adult mouse lung

应用
应用	This Anti-Polycystin-L Antibody is validated for use in WB, IC, IH for the detection of Polycystin-L.
主要应用	Immunohistochemistry Western Blotting Immunocytochemistry
应用说明	Western blot: 1:1,000 using ECL. The antibody reacts with the 90 kDa Polycystin1-L1 protein. Suggested blocking buffer is 10% normal goat serum (or same host as your secondary antibody), 1% BSA in 0.1M PBS with 0.05% Tween 20. Suggested dilution buffer is 1% normal goat serum (or same host as your secondary antibody), 1% BSA in 0.1M PBS with 0.05% Tween 20. Preferred gel percentage is 4-12% gradient gel. Immunocytochemistry: 1:1,000 Immunohistochemistry: 1:1,000 overnight at 2-8°C using a fluorescently labeled secondary antibody. Suggested fixative is 4% paraformaldehyde in 0.1M PBS (one hour). Suggested permeablization method is 0.05% Triton X-100 in dilution buffer. Suggested blocking buffer is 10% normal goat serum (or same host as your secondary antibody) and 1% BSA in 0.1M PBS. Suggested dilution buffer is 1% normal goat serum (or same host as your secondary antibody) and 1% BSA in 0.1M PBS. Optimal working dilutions must be determined by the end user.

生物信息
免疫原品种	Synthetic peptide from the N-terminal of human Polycystin-L1.
宿主	Rabbit
特异性	Polycystin-L
品种反应性	Mouse
抗体类型	Polyclonal Antibody
Entrez基因编号	NM_138295.2
Entrez基因汇总	This gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined.
基因符号	PK2L1 PKD2L1 Polycystic kidney disease-2 like 1 protein Polycystin-2 homolog
UniProt编号	Q9P0L9
UniProt汇总	FUNCTION: SwissProt: Q8TDX9 # May have a role in the heart and in the male reproductive system. SIZE: 2849 amino acids; 315435 Da SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). TISSUE SPECIFICITY: Detected in testis and in fetal and adult heart. SIMILARITY: SwissProt: Q8TDX9 ## Belongs to the polycystin family. & Contains 1 GPS domain. & Contains 2 PKD domains. & Contains 1 PLAT domain. & Contains 1 REJ domain.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

包装信息
数量	100 µL

merck millipore,默克密理博,AB9084,Anti-Polycystin-L Antibody

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