merck millipore,默克密理愽
  • merck millipore,默克密理博,05-23-3800,Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem

  • merck millipore,默克密理博,05-23-3800,Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem

    产品名称：Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem
    产品型号：05-23-3800
    A 21-amino acid polypeptide with potent vasoconstrictive action.

    merck millipore,默克密理博,05-23-3800,Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,05-23-3800,Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₀₉H₁₅₉N₂₅O₃₂S₅117399-94-7
    描述
    概述 A 21-amino acid polypeptide with potent vasoconstrictive action. Produces convulsions, arterial hypertension, and metabolic activation of periventricular white and gray matter. Its effects are mediated via L-type Ca2+ channels. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.
    产品目录编号 05-23-3800
    品牌系列 Calbiochem®
    同义词 ET-1, CSCSSLMDKECVYFCHLDIIW
    参考
    参考 Cesari, M., et al. 1996. Am. Heart J. 132, 1236.
    Gresser, O., et al 1996. Biochem. Biophys. Res. Commun. 224, 169.
    Murata, S., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1524.
    Hexum, T.D., et al. 1990. Biochem. Biophys. Res. Commun. 167, 294.
    Itoh, Y., et al. 1988. FEBS Lett. 231, 440.
    Yanagisawa, M., et al. 1988. Nature 332, 411.
    产品信息
    CAS号 117399-94-7
    具有ATP竞争性 N
    形式 White to off-white solid
    配方 Supplied as an acetate salt.
    Hill配方 C₁₀₉H₁₅₉N₂₅O₃₂S₅
    化学配方 C₁₀₉H₁₅₉N₂₅O₃₂S₅
    Molar Mass 2492
    肽序列 H-Cys¹-Ser-Cys³-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Phe-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
    可逆 N
    基于肽含量售出 Yes
    生物信息
    主靶 Potent vasoconstrictive action
    纯度 ≥96% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 5% Acetic Acid
    肽含量 Yes
    肽序列 H-Cys¹-Ser-Cys³-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Phe-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 36

    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.

    merck millipore,默克密理博,05-23-3800,Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem

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