merck millipore,默克密理博,05-23-2151,PACAP 27 Amide, Ovine - CAS 127317-03-7

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Merck Millipore 默克密理愽

merck millipore,默克密理博,05-23-2151,PACAP 27 Amide, Ovine - CAS 127317-03-7 - Calbiochem

经验配方	CAS号
C₁₄₂H₂₂₄N₄₀O₃₉S	127317-03-7

描述
概述	Increases cAMP levels in a dose-dependent manner (EC₅₀ = 4.7 nM). Increases tyrosine hydroxylase expression in chromaffin cells.
产品目录编号	05-23-2151
品牌系列	Calbiochem®
同义词	Pituitary Adenylate Cyclase Activating Polypeptide, HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH₂

参考
参考	Kobayashi, H., et al. 1994. Brain Res. 647, 145. Tatsuno, I., et al. 1990. Biochem. Biophys. Res. Commun. 168, 1027.

产品信息
CAS号	127317-03-7
具有ATP竞争性	N
形式	White to off-white solid
配方	Supplied as a trifluoroacetate salt.
Hill配方	C₁₄₂H₂₂₄N₄₀O₃₉S
化学配方	C₁₄₂H₂₂₄N₄₀O₃₉S
Molar Mass	3147.7
吸湿	Hygroscopic
肽序列	H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH₂
可逆	N
基于肽含量售出	Yes

生物信息
主靶	Increases cAMP levels
主靶IC₅₀	EC50 = 4.7 nM increasing cAMP levels in a dose-dependent manner
纯度	≥98% by HPLC

理化信息
细胞可渗透	N
溶解度	5% Acetic Acid
肽含量	Yes
肽序列	H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH₂

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

merck millipore,默克密理博,05-23-2151,PACAP 27 Amide, Ovine - CAS 127317-03-7 - Calbiochem

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