- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
Replacement Information Replacement Information 07-1208 is a recommended replacement for AB4068 重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H, M, R WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-1208 Replaces AB4068 品牌系列 Upstate
商名 - Upstate
描述 Anti-Gβ5 Antibody 背景信息 The Gβ5 (GNB5 guanine nucleotide binding protein (G protein), beta 5) is a G protein subunit present predominantly in the central nervous system. This protein appears to be expressed in two forms, one found in the brain of 39 kDa and one found in the retina of 44 kDa. It has also been found that Gβ5 associates tightly with RGS7, a member of the superfamily of negative regulators of G protein signaling. These complexes have been localized to most regions of the brain, whereas G1-4 exhibit no observable colocalization with RGS7, despite their widespread codistribution throughout similar neuronal networks. This antibody is specific for a peptide sequence within the D1 blade which is not found in Gβ1-4. 产品信息 格式 Purified 控制 - L6 Cell Lysate, plasma membranes from rat cerebrum.
演示 Purified rabbit polyclonal IgG in phosphate buffered saline with 0.08% sodium azide. 应用 应用 This Anti-Gβ5 Antibody is validated for use in WB for the detection of Gβ5. 主要应用 - Western Blotting
应用说明 Optimal working dilutions must be determined by end user. 生物信息 免疫原品种 Unique peptide sequence derived from the D1 blade of the Gβ5 protein. 表位 D1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes D1 area of Gβ5. 同种型 IgG 品种反应性 HumanMouseRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_006578.3
Entrez基因汇总 Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. 基因符号 - GB5
- GNB5
- FLJ37457
- FLJ43714
- Gbeta5
纯化方法 Purified UniProt编号 - O14775
UniProt汇总 FUNCTION: SwissProt: O14775 # Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
SIZE: 395 amino acids; 43566 Da
SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma. Component of the RGS9-1-Gbeta5 complex composed of RGS9 (isoform RGS9-1), Gbeta5 (GNB5) and RGS9BP (By similarity).
TISSUE SPECIFICITY: Expressed in multiple tissues.
SIMILARITY: SwissProt: O14775 ## Belongs to the WD repeat G protein beta family. & Contains 7 WD repeats.产品使用声明 质量保证 Routinely evaluated by Western Blot on L6 lysates.
Western Blot Analysis: 1:500 dilution of this lot detected G protein Gbeta5 on 10 μg of L6 lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,ABN64,Anti-RYK Antibody
下一件merck millipore产品：merck millipore,默克密理博,AB9884,Anti-Clathrin Light Chain Antibody
相关产品
merck millipore,默克密理博,218719,Casein Kinase I Inhibitor III, PF-4800567 - Calbiochem
merck millipore,默克密理博,70590,BacVector Insect Cell Medium - Novagen
merck millipore,默克密理博,14-595,PP1α Protein, 10 µg
merck millipore,默克密理博,ABN64,Anti-RYK Antibody
merck millipore,默克密理博,AB9884,Anti-Clathrin Light Chain Antibody
merck millipore,默克密理博,4500-0025,Guava Easy Check Kit for Flow Cytometry
merck millipore,默克密理博,71401,Rosetta™ 2(DE3)pLysS Singles™ Competent Cells - Novagen
merck millipore,默克密理博,05-23-2151,PACAP 27 Amide, Ovine - CAS 127317-03-7 - Calbiochem
