merck millipore,默克密理愽
  • merck millipore,默克密理博,H0XSTMAG-18K,MILLIPLEX MAP Human Oxidative Stress Magnetic Bead Panel - Cellular Metabolism Multiplex Assay

  • merck millipore,默克密理博,H0XSTMAG-18K,MILLIPLEX MAP Human Oxidative Stress Magnetic Bead Panel - Cellular Metabolism Multiplex Assay

    产品名称：MILLIPLEX MAP Human Oxidative Stress Magnetic Bead Panel - Cellular Metabolism Multiplex Assay
    产品型号：H0XSTMAG-18K
    The analytes available for this multiplex kit are: Catalase, PRX2, SOD1, SOD2, TRX1.

    merck millipore,默克密理博,H0XSTMAG-18K,MILLIPLEX MAP Human Oxidative Stress Magnetic Bead Panel - Cellular Metabolism Multiplex Assay

  • 产品介绍
  • merck millipore,默克密理博,H0XSTMAG-18K,MILLIPLEX MAP Human Oxidative Stress Magnetic Bead Panel - Cellular Metabolism Multiplex Assay

    重要规格表

    可用的分析物 品种反应性 主要应用 检测方法
    TRX1, Catalase, PRX2, SOD1, SOD2HMplexLuminex xMAP
    描述
    产品目录编号 H0XSTMAG-18K
    商名
    • MILLIPLEX
    描述 MILLIPLEX MAP Human Oxidative Stress Magnetic Bead Panel - Cellular Metabolism Multiplex Assay
    概述 The MILLIPLEX® MAP Human Oxidative Stress Magnetic Bead Panel (H0XSTMAG-18K)l is available in premix format only and is to be used for the simultaneous quantification of the following 5 analytes in cell or tissue lysate samples:
    • Catalase
    • PRX2 (Peroxiredoxin 2, PRDX2)
    • SOD1 (Superoxide dismutase 1, Superoxide dismutase [Cu-Zn])
    • SOD2 (Superoxide dismutase 2, MnSOD)
    • TRX1 (Thioredoxin)
    背景信息 Oxidative stress is the result of an imbalance between the production of reactive oxygen species (ROS) and the removal of their reactive intermediates. ROS are products of the Oxidative Phosphorylation pathway, and are chemically reactive oxygen molecules that include: hydrogen peroxide, nitric oxide, superoxide, and other hydroxyl radicals. In response to ROS damage, cells defend themselves by clearing the ROS molecules through enzymes such as superoxide dismutases, catalases, glutathione peroxidases and peroxiredoxins. In normal conditions, superoxide dismutase and catalase convert the superoxide and hydrogen peroxide into oxygen and water to minimize the damage to cells. When the ROS clearance pathway is impaired, accumulation of ROS can cause DNA damage, lipid peroxidation, and enzyme inactivation. ROS can be beneficial, as they are used by the immune system as a mechanism to attack and kill pathogens. Some ROS molecules are important for cell signaling as secondary messengers. The ability to monitor oxidative stress levels and the balance between ROS production and clearance within cells is a key element to the study of many diseases.
    产品信息
    检测方法 Luminex xMAP
    配置 Premixed
    精度（%）
    • Intra- and Inter-Assay CVs based on MFI values.
    • Inter-assay: < 15%
    • Intra-assay: < 10%
    板面类型 MAGNETIC Cellular Metabolism
    应用
    应用 The analytes available for this multiplex kit are: Catalase, PRX2, SOD1, SOD2, TRX1.
    主要应用
    • Multiplexing
    应用说明 • Two hours incubation is recommended for best results.
    • These assays require 25 µL diluted cell or tissue lysate.
    • We recommend using 5-20 µg total protein/well.
    生物信息
    品种反应性 Human
    可用的分析物
    • TRX1
    • Catalase
    • PRX2
    • SOD1
    • SOD2
    化验面板 Everything you need in a single kit.
    交叉反应性 There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within this panel.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Recommended storage for kit components is 2 - 8°C.
    包装信息
    数量 96-well plate

    merck millipore,默克密理博,H0XSTMAG-18K,MILLIPLEX MAP Human Oxidative Stress Magnetic Bead Panel - Cellular Metabolism Multiplex Assay

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