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merck millipore,默克密理博,05-1925,Anti-Lactoylglutathione lyase Antibody, clone Glo1a
产品名称：Anti-Lactoylglutathione lyase Antibody, clone Glo1a
产品型号：05-1925
Detect the Lactoylglutathione lyase protein using this Anti-Lactoylglutathione lyase, clone Glo1a validated for use in WB & ICC.
merck millipore,默克密理博,05-1925,Anti-Lactoylglutathione lyase Antibody, clone Glo1a
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB M Purified Monoclonal Antibody 描述 产品目录编号 05-1925 描述 Anti-Lactoylglutathione lyase Antibody, clone Glo1a Alternate Names - lactoyl glutathione lyase
- Glx I
- Ketone-aldehyde mutase
- S-D-lactoylglutathione methylglyoxal lyase
- glyoxalase I
- glyoxalase domain containing 1
背景信息 Lactoylglutathione lyase is a detoxifying enzyme involved in the glyoxalase system and is responsible for the catalysis of methylglyoxal and lactate. Lactoylglutathione lyase is also referred to as Glyoxalase I. 产品信息 格式 Purified 控制 - HeLa cell lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. 应用 应用 Detect the Lactoylglutathione lyase protein using this Anti-Lactoylglutathione lyase, clone Glo1a validated for use in WB & ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC. (Case Western Reserve University) 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human Lactoylglutathione lyase. 表位 Unknown 克隆 Glo1a 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody recognizes Lactoylglutathione lyase. 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Demonstrated to react with human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_006699.2
Entrez基因汇总 The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq]. 基因符号 - Methylglyoxalase
- GLO1
- Aldoketomutase
- GLOD1
- GLYI
纯化方法 Protein G purfied UniProt编号 - Q04760
UniProt汇总 FUNCTION: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
CATALYTIC ACTIVITY: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
COFACTOR: Binds 1 zinc ion per subunit.
PATHWAY: Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.
SUBUNIT STRUCTURE: Homodimer.
POLYMORPHISM: Exists in three separable isoforms which originate from two alleles in the genome. These correspond to two homodimers and one heterodimer composed of two subunits showing different electrophoretic properties.
SEQUENCE SIMILARITIES: Belongs to the glyoxalase I family.产品使用声明 质量保证 Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 0.1 µg/ml of this antibody detected Lactoylglutathione lyase on 10 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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