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Replacement Information Replacement Information 05-1115 is a recommended replacement for MAB5464 重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H, R ICC, WB M Ascites Monoclonal Antibody 描述 产品目录编号 05-1115 Replaces MAB5464 描述 Anti-SG2NA Antibody Alternate Names - Striatin 3
- Cell-cycle autoantigen SG2NA
背景信息 SG2NA, also known as Striatin 3, was identified as a human cancer auto-antigen and has not been implicated in vesicular trafficking and signal tranduction. It is highly related to striatin and zinedin (striatin 4). It is a cytoplasmic scaffolding protein that binds to Calmodulin and PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which appears to modulate PP2A activity. 产品信息 格式 Ascites 控制 - L6 cell lysate
演示 Mouse monoclonal IgG1 ascites containing 40% glycerol and 0.02% sodium azide. 应用 应用 Anti-SG2NA Antibody is an antibody against SG2NA for use in WB, IC & IP. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry: A previous lot of this antibody was used in immunocytochemistry at a 1:500 dilution.
Immunoprecipitation: A previous lot of this antibody was used in IP; 3 μL is a recommended as starting point for immunoprecipitation.
Optimal working dilutions must be determined by end user.
生物信息 免疫原品种 Synthetic peptide from SG2NA. 宿主 Mouse 特异性 Reacts with SG2NA. No cross reactivity with striatin. 同种型 IgG1 品种反应性 MouseHumanRat Species Reactivity Note Human, Rat and Mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001083893.1
基因符号 - SG2NA
- STRN3
- Striatin-3
- GS2NA
UniProt编号 - Q13033
UniProt汇总 FUNCTION: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
SUBUNIT: Interacts with protein phosphatase 2A (PP2A) (Potential).
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity).
ALTERNATIVE PRODUCTS: 2 named isoforms [FASTA] produced by alternative splicing. Additional isoforms seem to exist. Name Beta
Isoform ID Q13033-1
This is the isoform sequence displayed in this entry.
Name Alpha
Isoform ID Q13033-2
Features which should be applied to build the isoform sequence: VSP_006786.
SIMILARITY: Belongs to the WD repeat striatin family.
SIMILARITY: Contains 6 WD repeats.
CAUTION: Was originally (PubMed:7864889) thought to be nuclear.
产品使用声明 质量保证 Routinely evaluated by Western Blot on L6 lysates.
Western Blot Analysis: 1:500 dilution of this lot detected SG2NA on 10 μg of L6 lysates.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable at -20°C in undiluted aliquots for up to 1 year from date of receipt. For long-term storage, may be stored at -80°C.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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