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品种反应性 主要应用 宿主 格式 抗体类型 Rb, B, Ca, F, Fe, Fg, Gt, H, M, Po, R WB, ICC M Ascites Monoclonal Antibody 描述 产品目录编号 MAB1572 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Parvalbumin Antibody 背景信息 Parvalbumin is a calcium binding albumin protein. It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is localised in fast-contracting muscles, where its levels are highest, and in the brain and some endocrine tissues. Parvalbumin is present in GABAergic interneurons in the nervous system, predominantly expressed by chandelier and basket cells in the cortex. 产品信息 格式 Ascites 控制 - Brain tissue, Cultured neurons
演示 Ascites mouse monoclonal IgG1 liquid with 0.1% sodium azide. 应用 应用 Anti-Parvalbumin Antibody is an antibody against Parvalbumin for use in IC, IH(P) & WB. 主要应用 - Western Blotting
- Immunocytochemistry
应用说明 Immunohistochemistry:
A previous lot was used by indirect immunoperoxidase at 1:1,000-1:2,000 dilution. The antibody works on formalin fixed, paraffin embedded tissue sections of rat cerebellum from a previous lot. Fixation does not appear to affect MAB1572’s ability to detect parvalbumin.
Immunocytochemistry:
A previous lot of this antibody was used on cultured neurons.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Parvalbumin purified from frog muscle 克隆 PARV-19 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Parvalbumin. The antibody will react with parvalbumin from brain and muscle. By immunoblot it recognizes a protein of 12 kDa. The antibody is directed against an epitope at the first Ca+2-binding site and specifically stains the Ca+2 -bound form of parvalbumin. 同种型 IgG1 品种反应性 RabbitBovineCanineFishFelineFrogGoatHumanMousePigRat 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002854.2
Entrez基因汇总 The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. 基因符号 - D22S749
- PVALB
- MGC116759
- parvalbumin
纯化方法 Unpurified UniProt编号 - P20472
UniProt汇总 FUNCTION: SwissProt: P20472 # In muscle, the calcium-binding protein parvalbumin is thought to be involved in muscle relaxation.
SIZE: 110 amino acids; 12059 Da
SIMILARITY: SwissProt: P20472 ## Belongs to the parvalbumin family. & Contains 2 EF-hand domains.
MISCELLANEOUS: This protein binds two calcium ions.产品使用声明 质量保证 Routinely evaluated by Western Blot on mouse brain lysate.
Western Blot Analysis:
1:1000 dilution of this lot detected Parvalbumin on 10 μg of mouse brain lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20ºC from date of receipt. 包装信息 数量 100 µL
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