merck millipore,默克密理博,04-932,Anti-Calmodulin Binding Protein Epitope Tag Antibody, clone C16T, rabbit monoclonal

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merck millipore,默克密理博,04-932,Anti-Calmodulin Binding Protein Epitope Tag Antibody, clone C16T, rabbit monoclonal
产品名称：Anti-Calmodulin Binding Protein Epitope Tag Antibody, clone C16T, rabbit monoclonal
产品型号：04-932
This Anti-Calmodulin Binding Protein Epitope Tag Antibody, clone C16T is validated for use in WB for the detection of Calmodulin Binding Protein Epitope Tag.

merck millipore,默克密理博,04-932,Anti-Calmodulin Binding Protein Epitope Tag Antibody, clone C16T, rabbit monoclonal

产品介绍

merck millipore,默克密理博,04-932,Anti-Calmodulin Binding Protein Epitope Tag Antibody, clone C16T, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
Vrt	WB	Rb	Culture Supernatant	Monoclonal Antibody

描述
产品目录编号	04-932
Replaces	05-932
描述	Anti-Calmodulin Binding Protein Epitope Tag Antibody, clone C16T, rabbit monoclonal
Alternate Names	phosphorylase kinase, delta subunit calmodulin 1 calmodulin 1 (phosphorylase kinase, delta)
背景信息	Calmodulin Binding Protein (CBP) epitope tags are found in several E. coli expression vectors. Calmodulin (CaM), a small 17 kDa ubiquitous Ca2+ binding protein, acts as an intracellular Ca2+ receptor and transduces Ca2+ transients, usually in response to growth factors. It mediates the activity of a number of Ca2+ regulating enzymes, including protein kinases, phosphatases, nitric oxide synthases, and phosphodiesterase. Calmodulin is the principal intracellular calcium receptor. It is an acidic protein of 148 residues, and upon binding Ca2+, it in turn binds to short peptide sequences of many target proteins. Such interaction is thought to induce a conformational change on the target, resulting in its activation. Targets include the constitutively expressed nitric oxide synthases, the CaM kinases, and PP2B/Calcineurin.

产品信息
格式	Culture Supernatant
控制	Samples containing the calmodulin binding protein epitope tag.
演示	Cultured supernatant with 0.05% sodium azide.

应用
应用	This Anti-Calmodulin Binding Protein Epitope Tag Antibody, clone C16T is validated for use in WB for the detection of Calmodulin Binding Protein Epitope Tag.
主要应用	Western Blotting

生物信息
免疫原品种	KLH-conjugated, synthetic peptide corresponding to the Calmodulin Binding Protein (CBP) epitope tag found in several E. coli expression vectors.
表位	CBP epitope
克隆	C16T
宿主	Rabbit
特异性	Recombinant proteins containing the calmodulin binding protein epitope tag.
同种型	IgG
品种反应性	Vertebrates
Species Reactivity Note	Vertebrates.
抗体类型	Monoclonal Antibody
Entrez基因汇总	Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. They are identified by their occurrence in the cytosol or on membranes facing the cytosol and by a high affinity for calcium. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters.[supplied by OMIM]
基因符号	PHKD CALM CALML2 CAM CAM1 CAM2 CAM3 CAMB CAMC CAMI CAMIII CaM DD132
UniProt编号	P62158
UniProt汇总	FUNCTION: Calmodulin mediates the control of a large number of enzymes and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. SUBUNIT STRUCTURE: Interacts with MYO1C and RRAD By similarity. Interacts with CEP97, CEP110, TTN/titin and SRY. SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton › spindle. Cytoplasm › cytoskeleton › spindle pole. Note: Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules. PTM: Ubiquitination results in a strongly decreased activity By similarity.Phosphorylation results in a decreased activity By similarity. MISCELLANEOUS: This protein has four functional calcium-binding sites. SEQUENCE SIMILARITIES: Belongs to the calmodulin family. Contains 4 EF-hand domains.

产品使用声明
质量保证	Evaluated by Western Blot on lysates from transformed E. coli. Western Blot Analysis: 1:2,000 dilution of this antibody detected a recombinant protein containing the calmodulin binding protein epitope tag in lysates from transformed E. coli.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.