merck millipore,默克密理愽
  • merck millipore,默克密理博,04-1624,Anti-Centrin Antibody, clone 20H5

  • merck millipore,默克密理博,04-1624,Anti-Centrin Antibody, clone 20H5

    产品名称：Anti-Centrin Antibody, clone 20H5
    产品型号：04-1624
    Anti-Centrin Antibody, clone 20H5 is a Mouse Monoclonal Antibody for detection of Centrin also known as Caltractin isoform 2, EF-hand protein & has been validated in WB, IP, ICC.

    merck millipore,默克密理博,04-1624,Anti-Centrin Antibody, clone 20H5

  • 产品介绍
  • merck millipore,默克密理博,04-1624,Anti-Centrin Antibody, clone 20H5

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MICC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 04-1624
    描述 Anti-Centrin Antibody, clone 20H5
    Alternate Names
    • centrin, EF-hand protein, 1
    • Caltractin isoform 2
    • EF-hand protein
    • calcium binding protein
    • centrin 1
    背景信息 Centrin is a key regulator of centriole duplication. This protein is localized to the centrosome of interphase cells. During mitosis, centrin redistributes to the spindle poles, consistent with dynamic changes of the centrosome during the cell cycle. Current research suggests centrin exerts spatial and temporal control over centriole duplication through its role as a component of centriole precursor structures and through periodic cell-cycle specific changes in its abundance.
    产品信息
    格式 Purified
    控制
    • HeLa cell lysate
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
    应用
    应用 Anti-Centrin Antibody, clone 20H5 is a Mouse Monoclonal Antibody for detection of Centrin also known as Caltractin isoform 2, EF-hand protein & has been validated in WB, IP, ICC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Immunocytochemistry Analysis: Manandhar, G., et al. (1999). Cell Motil Cytoskeleton. 43(2):137-144.
    生物信息
    免疫原品种 Recombinant protein corresponding to the C-terminus of Chlamydomonas Centrin.
    表位 C-terminus
    克隆 20H5
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody recognizes the C-terminus of Centrin.
    同种型 IgG2aκ
    品种反应性 RatHumanMouse
    Species Reactivity Note Demonstrated to react in Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_004057
    Entrez基因汇总 The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.
    基因符号
    • Centrin-1
    • CEN1
    • CETN
    纯化方法 Protein G purfied
    UniProt编号
    • Q12798
    UniProt汇总 FUNCTION: Plays a fundamental role in microtubule-organizing center structure and function.

    SUBUNIT STRUCTURE: Monomer By similarity.

    SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton › centrosome. Note: Centrosome of interphase and mitotic cells.

    MISCELLANEOUS: Binds two moles of calcium per mole of protein.

    SEQUENCE SIMLARITIES: Belongs to the centrin family.

    Contains 4 EF-hand domains.
    产品使用声明
    质量保证 Evaluated by Western Blot in HeLa cell lysate.

    Western Blot Analysis: 1 µg/ml of this antibody detected Centrin on 10 µg of HeLa cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,04-1624,Anti-Centrin Antibody, clone 20H5

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