merck millipore,默克密理愽
  • merck millipore,默克密理博,SF-1121,PDGFRA; Human, Cyanine 5 RNA Detection Probe,SmartFlare

  • merck millipore,默克密理博,SF-1121,PDGFRA; Human, Cyanine 5 RNA Detection Probe,SmartFlare

    产品名称：PDGFRA; Human, Cyanine 5 RNA Detection Probe, SmartFlare
    产品型号：SF-1121
    Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare PDGFRA, Human, Cyanine 5, you can detect PDGFRA RNA levels within your cells.

    merck millipore,默克密理博,SF-1121,PDGFRA; Human, Cyanine 5 RNA Detection Probe,SmartFlare

  • 产品介绍
  • merck millipore,默克密理博,SF-1121,PDGFRA; Human, Cyanine 5 RNA Detection Probe,SmartFlare

    重要规格表

    Entrez Gene Number Species Reactivity
    NM_006206.4H
    描述
    产品目录编号 SF-1121
    商名
    • SmartFlare
    描述 PDGFRA; Human, Cyanine 5 RNA Detection Probe | SmartFlare
    Alternate Names
    • PDGFR-2
    • CD140A
    • PDGFR2
    背景信息 With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of PDGFRA; Human, Cyanine 5 RNA Detection Probe you can detect the presence of PDGFRA within your cells.
    PDGFR (Platelet-Derived Growth Factor Receptor) is a receptor tyrosine kinase for the PDGF family of growth factors. PDGF homo and hetero- dimmers (dimer of A (17 kDa) and B (14 kDa) chains (AA, AB, or BB)) bind to the two structurally related a and b PDGF Receptors (PDGFRa and PDGFRb). The type A PDGF Receptor binds all three PDGFs with high affinity, whereas the type B PDGF Receptor is selective for PDGF-BB. This binding results in the dimerization of the receptor and the subsequent kinase activation of the receptor tyrosine kinase (RTK) and its
    autophosphorylation. These phosphorylations allow for various proteins, such as PI3 Kinase, PLCg, and Grb2, to bind through their SH2 domains and transduce signals into the cell. The activation of PDGFFR triggers the intracellular loop and activates Ras, Erk1/2, and ROS. PDGFb has been implicated in embryonic development, angiogenesis, and development of tumors of glial origin.
    产品信息
    格式 Cyanine 5
    演示 Lyophilized
    应用
    应用 Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare PDGFRA, Human, Cyanine 5, you can detect PDGFRA RNA levels within your cells.
    主要应用
    • RNA Detection
    生物信息
    品种反应性 Human
    Entrez基因编号
    • NM_006206.4
    基因符号
    • PDGFRA
    产品使用声明
    质量保证 SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product.
    包装信息
    数量 250 reactions

    merck millipore,默克密理博,SF-1121,PDGFRA; Human, Cyanine 5 RNA Detection Probe,SmartFlare

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