merck millipore,默克密理博,SCC048,N27 Rat Dopaminergic Neural Cell Line

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Merck Millipore 默克密理愽

主要应用
CULT

描述
产品目录编号	SCC048
描述	N27 Rat Dopaminergic Neural Cell Line
Alternate Names	1RB3AN27 Cell Line Dopamine Neural Cells
背景信息	Parkinson’s disease is a neurodegenerative disorder of the central nervous system that affects more than 6 million people worldwide. The motor symptoms of Parkinson's disease result from the death of dopamine generating cells in the substantia nigra, a region of the midbrain. Numerous efforts have been made to slow the loss or replace these dopamine producing neurons in vivo. The N27 rat dopaminergic neuron cell line was harvested from E12 rat mesencephalic tissue and was transfected with SV40 to immortalize the cell line. The N27 cell line, when injected into the striata of 6-hydroxydopamine-lesioned rats (an animal model of PD) caused a time-dependent improvement in neurological deficits. This immortalized cell line has been carefully characterized in studies of dopamine biosynthesis, neurotoxicity and used as a dopaminergic neuron model for in vitro and in vivo studies.

产品信息
部件	1) ≥1X10⁶ viable N27 Rat Dopaminergic Neural Cell Line: (Catalog No. SCC048). Store in liquid nitrogen.
演示	Product is supplied frozen in 10% DMSO and 90% expansion medium.

应用
应用	The N27 rat dopaminergic neural cell line has been carefully characterized in studies of dopamine biosynthesis, neurotoxicity and used as a dopaminergic neuron model for in vitro and in vivo studies.
主要应用	Cell Culture

生物信息
品种	Rat
细胞系类型	Neural Lineage Cells Neural Stem Cells

产品使用声明
质量保证	• Each vial contains ≥ 1X10⁶ viable cells. • Cells are negative for mycoplasma contamination.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. This product contains genetically modified organisms (GMO). Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. This legislation obliges Merck-Millipore to request certain information about you and the establishment where the GMOs are being handled.

产品使用声明

质量保证

• Each vial contains ≥ 1X10⁶ viable cells.
• Cells are negative for mycoplasma contamination.

使用声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
This product contains genetically modified organisms (GMO). Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. This legislation obliges Merck-Millipore to request certain information about you and the establishment where the GMOs are being handled.

储存和货运信息
存储条件	N27 cells should be stored in liquid nitrogen. The cells can be passage for at least 10 passages without significantly affecting the cell marker expression and functionality.