merck millipore,默克密理博,MABT45,Anti-ICAM-2/CD102 (human) Antibody, clone CBR-IC2/2

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABT45
描述	Anti-ICAM-2/CD102 (human) Antibody, clone CBR-IC2/2
Alternate Names	CD102 antigen intercellular adhesion molecule 2
背景信息	Intercellular adhesion molecule 2 (ICAM-2, CD102) is a cell surface glycoprotein that is a part of the immunoglobulin superfamily. ICAM-2 is thought to act as a go-between during cell-cell adhesion interactions which are obligatory for immune system function. ICAM-2 may play a role in membrane to actin linkages. ICAM-2 may be a useful therapeutic target for oral squamous cell carcinoma.

产品信息
格式	Purified
控制	HUVEC cells
演示	Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	This Anti-ICAM-2/CD102 (human) Antibody, clone CBR-IC2/2 is validated for use in FC for the detection of ICAM-2/CD102 (human).
主要应用	Flow Cytometry
应用说明	Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (de Fougerolles, A., et al. (1991). J . Exp. Med. 174:253-267).

生物信息
免疫原品种	CHO cells expressing human ICAM-2.
克隆	CBR-IC22
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
同种型	IgG2aκ
品种反应性	Human
Species Reactivity Note	Demonstrated to react with human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_000864
基因符号	ICAM-2 ICAM2 CD102
纯化方法	Protein G Purified
UniProt编号	P13598
UniProt汇总	FUNCTION: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Expressed in endothelial cells and leukocytes. High levels found in lung. SEQUENCE SIMILARITIES: Belongs to the immunoglobulin superfamily. ICAM family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

产品使用声明
质量保证	Evaluated by Flow Cytometry in HUVEC cells. Flow Cytometry Analysis: 1 µg of this antibody detected ICAM-2 in HUVEC cells.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,MABT45,Anti-ICAM-2/CD102 (human) Antibody, clone CBR-IC2/2

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech