merck millipore,默克密理愽
  • merck millipore,默克密理博,MABT205,Anti-α-Tubulin Antibody, clone DM1A

  • merck millipore,默克密理博,MABT205,Anti-α-Tubulin Antibody, clone DM1A

    产品名称：Anti-α-Tubulin Antibody, clone DM1A
    产品型号：MABT205
    This Anti-α-Tubulin Antibody, clone DM1A is validated for use in Western Blotting, ICC, IHC for the detection of α-Tubulin.

    merck millipore,默克密理博,MABT205,Anti-α-Tubulin Antibody, clone DM1A

  • 产品介绍
  • merck millipore,默克密理博,MABT205,Anti-α-Tubulin Antibody, clone DM1A

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Ch, H, MIHC, WB, ICCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT205
    Replaces 04-1117
    描述 Anti-α-Tubulin Antibody, clone DM1A
    Alternate Names
    • Tubulin alpha-1 chain
    背景信息 Tubulin is one of the main components of the cytoskeleton. It is a heterodimeric structure consisting of interlocking alpha and beta chains. Like other cytoskeleton proteins, tubulin undergoes dynamic changes depending on the cellular context, which are mediated by binding and release of GDP/GTP. Tubulin proteins may also undergo post-translational modifications, and are essential to cellular transport and mitotic processes.
    产品信息
    格式 Purified
    控制
    • HeLa cell lysate.
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 This Anti-α-Tubulin Antibody, clone DM1A is validated for use in Western Blotting, ICC, IHC for the detection of α-Tubulin.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    • Immunocytochemistry
    应用说明 Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected α-tubulin in NIH/3T3, A431, and HeLa cells.

    Immunohistochemistry Analysis: A 1:10,000 dilution from a representative lot detected α-tubulin in normal human brain tissue, human brain cancer tissue, normal rat hippocampus tissue and normal rat cerebellum tissue.
    生物信息
    免疫原品种 Native chicken brain microtubules.
    克隆 DM1A
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG1κ
    品种反应性 ChickenHumanMouse
    Species Reactivity Note Demonstrated to react wtih Human and Mouse. Predicted to react with Chicken based on 100% sequence homology.
    抗体类型 Monoclonal Antibody
    纯化方法 Protein G purified
    UniProt编号
    • P02552
    UniProt汇总 FUNCTION: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.

    SUBUNIT STRUCTURE: Dimer of alpha and beta chains.

    SUBCELLULAR LOCATION: Cytoplasm > cytoskeleton.

    POST-TRANSLATIONAL MODIFICATION: Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.

    MISCELLANEOUS: There are at least seven alpha tubulin genes (alpha-1 to alpha-6, and alpha-8), and a pseudogene (alpha-7) in chicken.

    SEQUENCE SIMILARITIES: Belongs to the tubulin family.
    产品使用声明
    质量保证 Evaluated by Western Blot in HeLa cell lysate.

    Western Blot Analysis: 0.01 µg/mL of this antibody detected α-tubulin in 10 µg of HeLa cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABT205,Anti-α-Tubulin Antibody, clone DM1A

上一件merck millipore产品：merck millipore,默克密理博,AB947,Anti-Apolipoprotein E Antibody
下一件merck millipore产品：merck millipore,默克密理博,14-464,FGFR3 Protein, active, 10 µg


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