merck millipore,默克密理愽
  • merck millipore,默克密理博,475848,MIF Antagonist V, p425 - CAS 259444 - Calbiochem

  • merck millipore,默克密理博,475848,MIF Antagonist V, p425 - CAS 259444 - Calbiochem

    产品名称：MIF Antagonist V, p425 - CAS 259444 - Calbiochem
    产品型号：475848
    The MIF Antagonist V, p425, also referenced under CAS 2610-05-1, controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.

    merck millipore,默克密理博,475848,MIF Antagonist V, p425 - CAS 259444 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,475848,MIF Antagonist V, p425 - CAS 259444 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₃₄H₂₄N₆Na₄O₁₆S₄2610-05-1
    描述
    概述 A symmetrical bis-(amino, hydroxynaphthalenedisulfonate) compound that antagonizes macrophage migration inhibitory factor against receptor binding (IC50 = 810 nM against hMIF and CD74 interaction) and is more potent than ISO-1 (Cat. No. 475837) in suppressing MIF-induced cytokines and MMP-3 productions in human fibroblasts cultures (IC50 = ≤0.7 µM vs >5 µM). Unlike MIF Antagonists I-IV, p425 targets an area at the interface of two MIF trimers, distal to the active site.
    产品目录编号 475848
    品牌系列 Calbiochem®
    同义词 Sodium 6,6ʹ-(1E,1ʹE)-(3,3ʹ-dimethoxybiphenyl-4,4ʹ-diyl)bis(diazene-2,1-diyl)bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate)
    参考
    参考 Bai, F., et al. 2012. J. Biol. Chem. 287, 30653.
    产品信息
    CAS号 2610-05-1
    形式 Blue solid
    Hill配方 C₃₄H₂₄N₆Na₄O₁₆S₄
    Molar Mass 992.8
    吸湿 Hygroscopic
    可逆 Y
    结构配方图像
    生物信息
    主靶 MIF
    纯度 ≥95% by HPLC
    理化信息
    溶解度 H₂O
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,475848,MIF Antagonist V, p425 - CAS 259444 - Calbiochem

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