merck millipore,默克密理愽
  • merck millipore,默克密理博,MABT179,Anti-Osterix (SP7) Antibody, clone 6B12.1

  • merck millipore,默克密理博,MABT179,Anti-Osterix (SP7) Antibody, clone 6B12.1

    产品名称：Anti-Osterix (SP7) Antibody, clone 6B12.1
    产品型号：MABT179
    Detect the Osterix (SP7) protein using this Anti-Osterix (SP7), clone 6B12.1 validated for use in WB & IHC.

    merck millipore,默克密理博,MABT179,Anti-Osterix (SP7) Antibody, clone 6B12.1

  • 产品介绍
  • merck millipore,默克密理博,MABT179,Anti-Osterix (SP7) Antibody, clone 6B12.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT179
    描述 Anti-Osterix (SP7) Antibody, clone 6B12.1
    Alternate Names
    • Zinc finger protein osterix
    • Transcription factor Sp7
    背景信息 OSTERIX, or SP7, is a zinc finger-containing, osteoblast-specific transcription factor that is distinctly expressed in all developing bones, and is a key requirement for the differentiation of pre-osteoblasts into fully functional osteoblasts. While research on the actual functional mechanisms of OSTERIX is still on-going, current findings indicate that OSTERIX expression is induced by BMP-2 and Dlx5, and operates downstream of RUNX2, supporting its role in mesenchymal stem cell differentiation. Further studies also indicate that the OSTERIX transcription factor may also play a role in negatively regulating the Wnt/β-catenin signaling pathways and the proliferation of osteroblast cell types during embryonic osteogenesis.
    产品信息
    格式 Purified
    控制
    • SW1353 cell lysate
    演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
    应用
    应用 Detect the Osterix (SP7) protein using this Anti-Osterix (SP7), clone 6B12.1 validated for use in WB & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected Isocitrate dehydrogenase in rat tooth tissue. Nuclear staining may be observed in epithelial cells in some tissues.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human Osterix.
    克隆 6B12.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgMκ
    品种反应性 RatHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001166938
    基因符号
    • OSX
    • SP7
    纯化方法 Purified by ion-exchange chromatography
    UniProt编号
    • Q8TDD2
    产品使用声明
    质量保证 Evaluated by Western Blotting in SW1353 cell lysate.

    Western Blotting Analysis: 1.0 µg/mL of this antibody detected Osterix in 10 µg of SW1353 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABT179,Anti-Osterix (SP7) Antibody, clone 6B12.1

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