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品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABT176 描述 Anti-SOX-6, clone 3F4.1 Antibody Alternate Names - Transcription factor SOX-6
背景信息 The protein SOX-6 which is encoded by the gene SOX6, is a transcriptional activator that binds to the enhancer sequence in DNA of 5'AACAAT3' that is present on genes. SOX-6 plays a key role in development for several developmental systems including neurogenesis and skeleton formation. Additionally, SOX-6 is important in cardiocyte differentiation, cartilage development, cell morphogenesis, erythrocyte development, oligodendrocyte cell fate specification, positive regulation of cartilage development, positive regulation of chondrocyte differentiation, and positive regulation of mesenchymal stem cell differentiation. The activity of SOX-6 is mediated by sumoylation. SOX-6 is localized to the nucleus. SOX-6 is expressed in a wide variety of tissues both during development and in adult life, with the most abundant expression seen in skeletal muscle. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect SOX-6 using this Anti-SOX-6 antibody, clone 3F4.1 validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human SOX-6. 克隆 3F4.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001139283
基因符号 - SOX6
纯化方法 Protein G purified UniProt编号 - P35712
产品使用声明 质量保证 Evaluated by Western Blotting in Hek-293 nuclear extract.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected SOX-6 in 10 µg of Hek-293 nuclear extract.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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