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merck millipore,默克密理博,MABS731,Anti-PON1, clone EPR2893, Rabbit Monoclonal Antibody
产品名称:Anti-PON1, clone EPR2893, Rabbit Monoclonal Antibody
产品型号:MABS731
This Anti-PON1, clone EPR2893, Rabbit Monoclonal Antibody is validated for use in Western Blotting for the detection of PON1.
merck millipore,默克密理博,MABS731,Anti-PON1, clone EPR2893, Rabbit Monoclonal Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Unpurified Monoclonal Antibody 描述 产品目录编号 MABS731 描述 Anti-PON1, clone EPR2893, Rabbit Monoclonal Antibody Alternate Names - Serum aryldialkylphosphatase 1
- Serum paraoxonase/arylesterase 1
- PON 1
- Aromatic esterase 1
- A-esterase 1
- K-45
背景信息 Serum paraoxonase/arylesterase 1 (PON 1), also known as Aromatic esterase 1 (A-esterase 1) or K-45 or Serum aryldialkylphosphatase 1, and encoded by the gene name PON1 or PON, is an esterase and lactonase that is synthesized in the liver and secreted into blood, associated exclusively with high density lipoproteins that belongs to the paraoxonase family. PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. This protein has been implicated in protection from atherosclerosis. PON 1 possesses both antioxidant and anti-inflammatory properties. Protecting LDL and HDL from lipid peroxidation, PON 1 degrades specific oxidized cholesteryl esters and oxidized phospholipids contained in lipoproteins. PON1 is expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. Mutations in PON1 have been associated with Microvascular complications of diabetes 5. 产品信息 格式 Unpurified 演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol. 应用 应用 This Anti-PON1, clone EPR2893, Rabbit Monoclonal Antibody is validated for use in Western Blotting for the detection of PON1. 主要应用 - Western Blotting
应用说明 Produced in collaboration with Epitomics™ 生物信息 免疫原品种 Synthetic peptide corresponding to human PON1. 克隆 EPR2893 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 同种型 IgG 品种反应性 Human Species Reactivity Note Human 抗体类型 Monoclonal Antibody 基因符号 - PON
- PON1
纯化方法 Unpurified UniProt编号 - P27169
产品使用声明 质量保证 Evaluated by Western Blotting in human fetal kidney, human ovary cancer, human fetal liver, and human plasma lysates.
Western Blotting Analysis: A 1:10,000-50,000 dilution of this antibody detected PON1 in human fetal kidney, human ovary cancer, human fetal liver, and human plasma lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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